Decreased LINE-1 methylation levels in aldosterone-producing adenoma

Chen Chen; Xiaoyu Zhou; Jing Jing; Jing Cheng; Yu Luo; Jiachao Chen; Xi Xu; Fei Leng; Xiaomu Li; Zhiqiang Lu
July 2014
International Journal of Clinical & Experimental Pathology;2014, Vol. 7 Issue 7, p4104
Academic Journal
No abstract available.


Related Articles

  • DNA methylation changes in ex-adenoma carcinoma of the large intestine. Kwon, Hyeong-Ju; Kim, Jung; Bae, Jeong; Cho, Nam-Yun; Kim, Tae-You; Kang, Gyeong; Kim, Jung Ho; Bae, Jeong Mo; Kang, Gyeong Hoon // Virchows Archiv;Oct2010, Vol. 457 Issue 4, p433 

    Ex-adenoma carcinoma (EAC) is a carcinoma with contiguous adenoma element in its vicinity which provides a morphological evidence for adenoma-carcinoma sequence. During multistep colorectal carcinogenesis, promoter CpG island hypermethylation has been known to increase in a stepwise manner...

  • Aldosterone Induced Galectin-3 Secretion In Vitro and In Vivo: From Cells to Humans. Lin, Yen-Hung; Chou, Chia-Hung; Wu, Xue-Ming; Chang, Yi-Yao; Hung, Chi-Sheng; Chen, Ying-Hsien; Tzeng, Yu-Lin; Wu, Vin-Cent; Ho, Yi-Lwun; Hsieh, Fon-Jou; Wu, Kwan-Dun // PLoS ONE;Sep2014, Vol. 9 Issue 9, p1 

    Context: Patients with primary aldosteronism are associated with increased myocardial fibrosis. Galectin-3 is one of the most important mediators between macrophage activation and myocardial fibrosis. Objective: To investigate whether aldosterone induces galectin-3 secretion in vitro and in...

  • Pancreatic Tumors in Multiple Endocrine Neoplasia Type 1. Doherty, Gerard // World Journal of Surgery;May2006, Vol. 30 Issue 5, p663 

    The article focuses on the results of unilateral adrenalectomy in patients with aldosterone-producing adenoma or unilateral primary adrenal hyperplasia. Adrenal venous sampling is the reference standard test to differentiate unilateral from bilateral disease in patients with primary...

  • Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways. Dallosso, A R; Øster, B; Greenhough, A; Thorsen, K; Curry, T J; Owen, C; Hancock, A L; Szemes, M; Paraskeva, C; Frank, M; Andersen, C L; Malik, K // Oncogene; 

    Loss of tumour suppressor gene function can occur as a result of epigenetic silencing of large chromosomal regions, referred to as long-range epigenetic silencing (LRES), and genome-wide analyses have revealed that LRES is present in many cancer types. Here we utilize Illumina Beadchip...

  • Promoter methylation of Wnt-antagonists in polypoid and nonpolypoid colorectal adenomas. Voorham, Quirinus J. M.; Janssen, Jerry; Tijssen, Marianne; Snellenberg, Suzanne; Mongera, Sandra; van Grieken, Nicole C. T.; Grabsch, Heike; Kliment, Martin; Rembacken, Bjorn J.; Mulder, Chris J. J.; van Engeland, Manon; Meijer, Gerrit A.; Steenbergen, Renske D. M.; Carvalho, Beatriz // BMC Cancer;2013, Vol. 13 Issue 1, p1 

    Background Nonpolypoid adenomas are a subgroup of colorectal adenomas that have been associated with a more aggressive clinical behaviour compared to their polypoid counterparts. A substantial proportion of nonpolypoid and polypoid adenomas lack APC mutations, APC methylation or chromosomal loss...

  • Response to ‘Diagnosis of aldosterone producing adenomas’. Chung, S.-D.; Wu, V.-C.; Liu, K.-L.; Huang, K.-H.; Chueh, S.-C.; Yu, H.-J. // Kidney International;Feb2008, Vol. 73 Issue 3, p363 

    A response by S. D. Chung and colleagues to a letter to the editor about their article "Diagnosis of bilateral aldosterone-producing adenomas in the 2007 issue is presented.

  • Medical management of aldosterone-producing adenomas. Ghose, P.; Hall, Philip M.; Ghose, R P; Hall, P M; Bravo, E L // Annals of Internal Medicine;07/20/99, Vol. 131 Issue 2, p105 

    Background: No data are available on the long-term medical management of aldosterone-producing adenomas.Objective: To demonstrate the efficacy of medical management of aldosterone-producing adenomas in terms of blood pressure and serum potassium concentration and to...

  • Silencing of RASSF3 by DNA Hypermethylation Is Associated with Tumorigenesis in Somatotroph Adenomas. Peng, Hu; Liu, Huanhai; Zhao, Shuwei; Wu, Jian; Fan, Jingping; Liao, Jianchun // PLoS ONE;Mar2013, Vol. 8 Issue 3, p1 

    The pathogenic mechanisms underlying pituitary somatotroph adenoma formation, progression are poorly understood. To identify candidate tumor suppressor genes involved in pituitary somatotroph adenoma tumorigenesis, we used HG18 CpG plus Promoter Microarray in 27 human somatotroph adenomas and 4...

  • Thrombospondin-4 is a putative tumour-suppressor gene in colorectal cancer that exhibits age-related methylation. Greco, Sonia A.; Chia, June; Inglis, Kelly J.; Cozzi, Sarah-Jane; Ramsnes, Ingunn; Buttenshaw, Ronald L.; Spring, Kevin J.; Boyle, Glen M.; Worthley, Daniel L.; Leggett, Barbara A.; Whitehall, Vicki L. J. // BMC Cancer;2010, Vol. 10, p494 

    Background: Thrombospondin-4 (THBS4) is a member of the extracellular calcium-binding protein family and is involved in cell adhesion and migration. The aim of this study was to evaluate the potential role of deregulation of THBS4 expression in colorectal carcinogenesis. Of particular interest...

  • Incidentally discovered pheochromocytoma and aldosterone-producing adenoma in the same adrenal gland. Negro, Aurelio; Santi, Rosaria; Giunta, Alessandro; Lococo, Filippo; Gemelli, Giuseppe; Piana, Simonetta; Ragazzi, Moira; Cavalieri, Simonetta // Italian Journal of Medicine;2015, Vol. 9 Issue 3, p294 

    Simultaneous occurrence of pheochromocytoma and aldosterone-producing adrenocortical tumor has been rarely reported in patients with symptoms or findings suggestive for both neoplasms. Herein, we report and discuss on a challenging case of synchronous pheochromocytoma and aldosterone-producing...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics