Desmoid Tumor of the Thigh with Multiple Recurrences

Livadariu, Roxana; Timofte, Daniel; Blaj, Mihaela; Ciobanu, Delia; Ionescu, Lidia; Dănilă, Radu
January 2014
Jurnalul de Chirurgie;2014, Vol. 10 Issue 1, p86
Academic Journal
Background: Desmoid tumors are rare neoplasms of uncertain etiology arising from fascial or deep musculo-aponeurotic structures. Although with benign histological appearance and no metastatic potential, desmoid tumors are locally aggressive tumors with a high rate of local recurrence. Case Report: The case of a 47 years old woman repeatedly operated for a recurrent desmoid tumor of the right thigh is presented. The initial radical excision was followed by adjuvant radiotherapy but local recurrence was diagnosed one year after. The pathology report revealed aspects of desmoid tumor. The patient was reoperated and subsequently referred for chemo- and hormonal therapy. A second recurrence occurred 20 months later and the patient was again operated with microscopic tumor free margins and positive long term outcome. Conclusion: Desmoid tumors are benign tumors with unpredictable natural history. Best management involves a multidisciplinary approach. Concerning diagnosis, the best approach is performing a MRI examination. Wide surgical resection with adjuvant radiation therapy remains the main treatment option for local control.


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