TITLE

Electrochemical Oxidation of Acetyl Salicylic Acid and its voltammetric sensing in real samples at a sensitive edge plane Pyrolytic Graphite Electrode modified with Graphene

AUTHOR(S)
Kruanetr, Senee; Pollard, Pat; Fernandez, Carlos; Prabhu, Radhakrishna
PUB. DATE
October 2014
SOURCE
International Journal of Electrochemical Science;2014, Vol. 9 Issue 10, p5699
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We present in this manuscript for the first time the electrochemical oxidation of acetyl salicylic acid and its voltammetric sensing in real samples at a sensitive edge plane pyrolitic graphite electrode (EPPGE) modified with graphene. The electrochemical response of the sensor was improved compared to edge plane pyrolytic graphite electrode and displayed an excellent analytical performance for the detection of acetyl salicylic acid. These characteristics were attributed to the high acetyl salicylic acid loading capacity on the electrode surface and the outstanding electric conductivity of graphene. A linear response was obtained over a range of acetyl salicylic acid concentrations from 10 nM to 100nM into a pH 4 buffer solution (N defined as the sample size N = 7) with a detection limit of 3 nM based on (3-σ/slope). The methodology is shown to be useful for quantifying low levels of acetyl salicylic acid in a buffer solution. The protocol is also shown to be applicable for the sensing of acetyl salicylic acid in human oral fluid samples. A linear response was obtained from 30nM to 150 nM into a human oral fluid solution (N = 7) with a detection limit of 17.3nM. Cyclic Voltammetry (CV) using EPPG modify with graphene has been employed in the proposed method for the determination of ASA in drug preparations and human oral fluid.
ACCESSION #
97184958

 

Related Articles

  • Electromagnetic Properties of Graphene-like Films in Ka-Band. Voronovich, Sofia; Paddubskaya, Alesya; Batrakov, Konstantin; Kuzhir, Polina; Maksimenko, Sergey; Kaplas, Tommi; Svirko, Yuri // Applied Sciences (2076-3417);Jun2014, Vol. 4 Issue 2, p255 

    We studied electromagnetic properties of pyrolytic carbon (PyC) films with thicknesses from 9 nm to 110 nm. The PyC films consisted of randomly oriented and intertwined graphene flakes with a typical size of a few nanometers were synthesized by chemical vapor deposition (CVD) at 1100 °C on a...

  • Use of Waste Polyethylene as a Source of Reducing Agent for Metal Oxide Reduction: A Case Study on NiO. Altay, M. Cumbul; Eroglu, S. // JOM: The Journal of The Minerals, Metals & Materials Society (TM;Jul2019, Vol. 71 Issue 7, p2338 

    This study introduces a novel way of using pyrolytic gas generated by the pyrolysis of waste high-density polyethylene (HDPE) for metal oxide reduction. A case study on NiO was carried out to reveal the feasibility of the method. Thermodynamic calculations were performed to guide and better...

  • Local conductivity of graphene oxide study by conductive atomic force microscope. Li, Jun; Wu, Jie; Huang, Zongyu; Qi, Xiang; Zhong, Jianxin // Journal of Applied Physics;12/7/2019, Vol. 126 Issue 21, p1 

    In this paper, a Conductive Atomic Force Microscope was used to measure the current distribution image of monolayer graphene oxide (GO) and I/V curves of different types of points in current distribution. Graphene oxide (GO) was prepared by a modified Hummer's method and deposited on highly...

  • Effect of conditions of formation of composite pyrographite/Nafion-polyaniline-Pt anode upon electrooxidation of methanol. Andreev, V.; Ehrenburg, M.; Bogdanovskaya, V. // Protection of Metals & Physical Chemistry of Surfaces;Sep2014, Vol. 50 Issue 5, p632 

    The effect of the conditions of formation (regime of formation and sequence of deposition of composite components, pH of the solution) of a multicomponent composite anode including polyaniline, Nafion, and platinum on the activity of such an anode in the course of electrocatalytic oxidation of...

  • BiFeO3 nanodots prepared via dip-pen lithography on Nb-doped SrTiO3 and highly ordered pyrolytic graphite substrates. Kim, Woo-Hee; Yeog Son, Jong // Applied Physics Letters;7/29/2013, Vol. 103 Issue 5, p052905 

    Ferroelectric BiFeO3 (BFO) nanodots were prepared on two substrate types, a Nb-doped SrTiO3 (Nb:STO) and a highly ordered pyrolytic graphite (HOPG), using elaborately controllable dip-pen nanolithography (DPN) technology. The lateral dimension and thickness of the formed BFO nanodots exhibited...

  • Molecular orientation of copper phthalocyanine thin films on different monolayers of fullerene on SiO2 or highly oriented pyrolytic graphite. Chenggong Wang; Xiaoliang Liu; Congcong Wang; Xumei Xu; Youzhen Li; Fangyan Xie; Yongli Gao // Applied Physics Letters;3/23/2015, Vol. 106 Issue 12, p1 

    The interface electronic structures of copper phthalocyanine (CuPc) have been studied using ultraviolet photoemission spectroscopy as different monolayers of C60 were inserted between CuPc and a SiO2 or highly ordered pyrolytic graphite (HOPG) substrate. The results show that CuPc has standing...

  • Orientation-dependent ionization potential of CuPc and energy level alignment at C60/CuPc interface. Wang, Chenggong; Turinske, Alexander J.; Gao, Yongli // Applied Physics B: Lasers & Optics;Dec2013, Vol. 113 Issue 3, p361 

    The electronic structure evolution of interfaces of fullerene (C 60) with copper phthalocyanine (CuPc) on highly oriented pyrolytic graphite (HOPG) and on native silicon oxide has been investigated with ultraviolet photoemission spectroscopy and inverse photoemission spectroscopy. The LUMO edge...

  • XPS study of gold oxidation with nitrogen dioxide in model Au/C samples. Kalinkin, A.; Smirnov, M.; Bukhtiyarov, A.; Bukhtiyarov, V. // Kinetics & Catalysis;Nov2015, Vol. 56 Issue 6, p796 

    The interaction of NO with model samples obtained by the gold sputter deposition onto the surface of highly oriented pyrolytic graphite (HOPG) has been studied by X-ray photoelectron spectroscopy (XPS). It has been shown that 3D metal particles characterized by an Au4 f binding energy (BE) of...

  • Synthesis and characterisation of reduced graphene oxide from graphite waste and HOPG. González-Barriuso, M.; Yedra, A.; Mantilla, P.; Manteca-Martínez, C. // Materials Research Innovations;Apr2015, Vol. 19 Issue 3, p192 

    Water soluble graphene oxide nanoplatelets and reduced graphene oxide were prepared from highly oriented pyrolytic graphite (HOPG) and from graphite waste powder. This graphite waste has been used to reuse an industrial waste product and therefore, to reduce production cost of the graphene. A...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics