TITLE

Wnt signalling required for expansion of neural crest and CNS progenitors

AUTHOR(S)
Ikeya, Makoto; Lee, Scott M. K.
PUB. DATE
October 1997
SOURCE
Nature;10/30/1997, Vol. 389 Issue 6654, p966
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Presents research demonstrating that in the absence of both Wnt-1 and Wnt-3a genes there is a marked deficiency in neural crest derivatives and a pronounced reduction in dorsolateral neural precursors within the neural tube of a vertebrate central nervous system (CNS). Coexpression of Wnt-1 and Wnt-3a; Cause of phenotypes; Local Wnt signaling regulating the expansion of dorsal neural precursors; Model for Wnt action. INSET: Methods..
ACCESSION #
9711120220

 

Related Articles

  • The plastic face. Pasqualetti, Massimo; Rijli, Filippo M. // Nature;4/4/2002, Vol. 416 Issue 6880, p493 

    Focuses on the formation of face in vertebrates. Contribute of neural crest cells to the facial structure of the vertebrates; Presence of neural crest cells in posterior part of the brain to help in the formation of neck bones; Division of neural tube to give rise to the brain.

  • A girl with spina bifida, an extra leg, and ectopic intestinal loops – a “foetus in foetu” or a whim of the neural crest? Lende, G.; Wendemu, W.; Mørk, S.; Wester, K. // Acta Neurochirurgica;Oct2007, Vol. 149 Issue 10, p1071 

    This article describes a girl with an extra leg attached to her lower back, combined with a spina bifida and a myelomeningocele. Despite lacking sensory or motor functions, the leg grew proportionately with the rest of the body. The bony structures were almost normal. A cross section showed fat...

  • The neural crest and neural crest cells: discovery and significance for theories of embryonic organization. Hall, Brian K. // Journal of Biosciences;Dec2008, Vol. 33 Issue 5, p781 

    The neural crest has long fascinated developmental biologists, and, increasingly over the past decades, evolutionary and evolutionary developmental biologists. The neural crest is the name given to the fold of ectoderm at the junction between neural and epidermal ectoderm in neurula-stage...

  • PO-RR-096-SA.  // Physical Therapy;May1997, Vol. 77 Issue 5, pS32 

    Presents an abstract of a paper entitled `Effects of Pressure on Reciprocal Inhibition,' by E.A. Perkins, L.M. Sell et al, presented at the Physical Therapy `97: Scientific Meeting and Exposition of the American Physical Therapy Association.

  • Perturbation of Hoxb5 signaling in vagal and trunk neural crest cells causes apoptosis and neurocristopathies in mice. Kam, M K M; Cheung, M C H; Zhu, J J; Cheng, W W C; Sat, E W Y; Tam, P K H; Lui, V C H // Cell Death & Differentiation;Feb2014, Vol. 21 Issue 2, p278 

    Neural crest cells (NCCs) migrate from different regions along the anterior-posterior axis of the neural tube (NT) to form different structures. Defective NCC development causes congenital neurocristopathies affecting multiple NCC-derived tissues in human. Perturbed Hoxb5 signaling in vagal NCC...

  • Development: Taking orders from above. Wood, Heather // Nature Reviews Neuroscience;Apr2004, Vol. 5 Issue 4, p255 

    Presents evidences that transcription factors Msx1 and Msx3, which are believed to be downstream targets of bone morphogenetic protein (Bmp) signaling, regulate distinct phases of development in the dorsal neural tube. Approach used by researchers to compare the effects of Bmp signaling during...

  • PleiotRHOpic. Fort, Philippe; Théveneau, Eric // Small GTPases;2014, Vol. 5 Issue 1, pN.PAG 

    Neural Crest (NC) cells are a multipotent migratory stem cell population unique to vertebrates, which contributes extensively to the formation of a wide array of neural and non-neural structures in the embryo. NC cells originate in the ectoderm at the border of the neural tube, undergo an...

  • Induced Pluripotent Stem Cells Generated from P0-Cre;Z/EG Transgenic Mice. Ogawa, Yasuhiro; Eto, Akira; Miyake, Chisato; Tsuchida, Nana; Miyake, Haruka; Takaku, Yasuhiro; Hagiwara, Hiroaki; Oishi, Kazuhiko // PLoS ONE;9/18/2015, Vol. 10 Issue 9, p1 

    Neural crest (NC) cells are a migratory, multipotent cell population that arises at the neural plate border, and migrate from the dorsal neural tube to their target tissues, where they differentiate into various cell types. Abnormal development of NC cells can result in severe congenital birth...

  • A Novel Role for Lh3 Dependent ECM Modifications during Neural Crest Cell Migration in Zebrafish. Banerjee, Santanu; Isaacman-Beck, Jesse; Schneider, Valerie A.; Granato, Michael // PLoS ONE;Jan2013, Vol. 8 Issue 1, Special section p1 

    During vertebrate development, trunk neural crest cells delaminate along the entire length of the dorsal neural tube and initially migrate as a non-segmented sheet. As they enter the somites, neural crest cells rearrange into spatially restricted segmental streams. Extracellular matrix...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics