TITLE

`Pacman' enzyme gobbles antibiotics

AUTHOR(S)
Brown, C. J.
PUB. DATE
September 1997
SOURCE
CMAJ: Canadian Medical Association Journal;09/01/97, Vol. 157 Issue 5, p504
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Reports the discovery of the structure of aminoglycoside kinase enzymes. How the enzyme mechanism acts like the arcade game called Pacman, according to Albert Berghuis, assistant professor of biochemistry at McMaster University in Canada; The discovery as providing clues to antibiotic resistance in hospitals; The enzymes similarity to eukaryotic protein kinases.
ACCESSION #
9709112536

 

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