TITLE

Heart-valve disease linked to common diet drug

AUTHOR(S)
Brown, C. J.
PUB. DATE
August 1997
SOURCE
CMAJ: Canadian Medical Association Journal;08/15/97, Vol. 157 Issue 4, p362
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Describes a study to be published in the New England Journal of Medicine which observed serious heart-valve damage in patients treated for obesity with fenfluramine and phentermine (fen-phen). Research at Mayo Clinic, Rochester, Minnesota; Details of study; Drugs' effect on circulating serotonin levels; Reaction from Health Canada's Therapeutic Products Directorate.
ACCESSION #
9708221602

 

Related Articles

  • Fenfluramine and phentermine added to list of causes of valvular heart disease. Dale, David C.; Federman, Daniel D. // Cortlandt Forum;03/25/98, Vol. 11 Issue 3, p26 

    Reports on the combined use of fenfluramine and phentermine as an added cause to valvular heart disease. Incidence and reversibility of valvular disease; List of iatrogenic causes of valvular heart disease; Chordal rupture and valvular incompetence as a possible result of myocardial biopsy.

  • Groups argue significance of 'fen-phen' study.  // Modern Medicine;Aug97, Vol. 65 Issue 8, p4 

    Reports on reactions to a study which will be published in the `New England Journal of Medicine' which found that women who were taking fenfluramine and phentermine developed valvular problems. Food & Drug Administration's issuance of an alert to physicians to check patients taking the...

  • Diet drug `fen-phen'  // Ebony;Sep1997, Vol. 52 Issue 11, p21 

    Provides information about the diet-drug combination of fenfluramine and phentermine, commonly known as `fen-pen'. How the drug works; Drug indications; Side effects of the drug; Advice before taking the drug.

  • The demise of diet pills. Napier, Kristine // Prevention;Dec97, Vol. 49 Issue 12, p40 

    Looks at the demise of diet pills as of November 1997. The reported cases of rare heart-valve disease in women who took the weight-loss combo fen-phen (fenfluramine and phentermine) in July 1997; The side effects of Redux; The voluntary removal of both drugs from the market in September 1997...

  • Health-hazard hype--deflated. Benjamin, Caren // Self;Mar2000, Vol. 22 Issue 3, p80 

    Presents samples of sensationalized health-hazard news in the United States. Side-effects of anti-obesity drugs fenfluramine and phentermine; Health problems caused by Norplant, an implantable contraceptive; Truth about the news on cancer-causing pesticides.

  • Fenfluramine link to heart valves strong.  // Healthy Weight Journal;Jan/Feb2001, Vol. 15 Issue 1, p2 

    Discusses the relationship between fenfluramine appetite-suppressant drugs and heart valves disorders. Prevalence of the disorder to users; Consequences of drug use.

  • After fen-phen. Cowley, Geoffrey; Springen, Karen // Newsweek;9/29/1997, Vol. 130 Issue 13, p46 

    Discusses the recall of the anti-obesity drugs fenfluramine (Pondimin) and dexfenfluramine (Redux). Inconclusive evidence of damage to heart valves in users of the drugs; Cost to American Home Products, the conglomerate that makes Pondimin and distributes Redux, of the recall; Pondimin's...

  • Interim recommendations issued for patients exposed to fenfluramine and dexfenfluramine.  // JAMA: Journal of the American Medical Association;12/03/97, Vol. 278 Issue 21, p1728 

    Discusses interim recommendations from the US Food and Drug Administration and other agencies for patients exposed to two appetite suppressant drugs, fenfluramine and dexfenfluramine. Withdrawal of the drugs, marketed under the trade names Pondimin and Redux, due to large number of patients who...

  • Cardiac valvulopathy associated with exposure to fenfluramine or dexfenfluramine: US Department of..  // JAMA: Journal of the American Medical Association;12/03/97, Vol. 278 Issue 21, p1729 

    Discusses cases of valvular heart disease in women treated with two appetite suppressants, fenfluramine and dexfenfluramine. Summary of date used by the US Food and Drug Administration in its decision to request voluntary withdrawal of these drugs from the market; Interim public health...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics