Modulation of plasma antioxidant activity in weaned piglets by plant polyphenols

Zhang, Hai J.; Jiang, Xian R.; Lumbreras, Ana E. Valdez; Comi, Marcello; Alborali, Giovanni; Savoini, Giovanni; Dell'Orto, Vittorio; Bontempo, Valentino
April 2014
Italian Journal of Animal Science;2014, Vol. 13 Issue 2, p424
Academic Journal
This study was conducted to evaluate the effect of plant polyphenols (PP) on antioxidant activity in weaned piglets. First, a uniform design, one optimising an experimental technique that can rationally arrange the concentrations of mixture components, was used to obtain the best PP mixture of apple, grape seed, green tea and olive leaf polyphenols based on in vitro antioxidant capacity and inhibitory action on bacterial growth. Second, the optimised PP mixture was tested in vivo with an efficacy trial on piglets. The optimal effects of the mix were observed in vitro when apple, grape seed, green tea, olive leaf polyphenols and a carrier (silicon dioxide) accounted for 16.5, 27.5, 30, 2.5 and 23.5%, respectively, of the mixture. Forty-eight weaned piglets were randomly allocated to two dietary treatments (6 replicates of 4 piglets each per treatment) and fed a control diet (CTR) or CTR supplemented with 0.1% of the optimised PP mixture. Dietary PP did not affect growth performance compared to the CTR group. Plasma total protein, urea nitrogen and lysozyme content were not affected by dietary treatment. No differences of E. coli or Clostridia counts in the faeces and caecum content between the CTR and PP groups were observed. A reduced malondialdehyde concentration in the PP group was observed on day 21 compared to the CTR group (P=0.02). In conclusion, the prepared PP mixture has the potential to improve plasma antioxidant activity.


Related Articles

  • Measurement of total antioxidant response in colorectal cancer using a novel automated method. Özgönül, Abdullah; Aksoy, Nurten; Dilmeç, Fuat; Uzunköy, Ali; Aksoy, Şahin // Turkish Journal of Medical Sciences;2009, Vol. 39 Issue 4, p503 

    Aim: The aim of this study was to compare the antioxidative status in patients with colorectal cancer and healthy controls, based on measurements made using a novel method. Materials and Methods: The study was conducted between 2005 and 2007, and included 30 patients with colorectal cancer and...

  • PHENOLIC COMPOSITION, ANTIOXIDANT CAPACITY OF SALVIA VERTICCILATA AND EFFECT ON MULTIDRUG RESISTANT BACTERIA BY FLOW-CYTOMETRY. Tekeli, Yener; Karpuz, Esra; Danahaliloglu, Hatice; Bucak, Serbay; Guzel, Yelda; Erdmann, Helmuth // African Journal of Traditional, Complementary & Alternative Medi;2014, Vol. 11 Issue 4, p147 

    Background: Antioxidants are of great importance for preventing oxidative stress that may cause several degenerative diseases. Studies have indicated phytochemicals have high free-radical scavenging activity, which helps to reduce the risk of chronic diseases. The aim of the present study is the...

  • Lysozyme Activity in the Plasma of Rodents Infected With Their Homologous Trypanosomes. Maraghi, S.; Molyneux, D. H.; Wallbanks, K. R. // Iranian Journal of Parasitology;2012, Vol. 7 Issue 4, p86 

    Background: In this study the concentration of lysozyme in blood plasma of Microtus agrestis, Clethrinomys glareolus, Apodemus sylvaticus, BK rats and outbred white mice before and after infection with culture forms of Trypanosoma microti, T, evotomys, T. grosi, T. lewisi and T. musculi...

  • Peculiarities of the lysozyme content in cods (order Gadiformes) and flatfish (order Pleuronectiformes). Subbotkina, T.; Subbotkin, M. // Journal of Evolutionary Biochemistry & Physiology;Jul2013, Vol. 49 Issue 4, p415 

    There was analyzed the content of lysozyme-the parameter of the non-specific immunity-in kidney, liver, spleen, and blood serum in 8 fish species of orders Gadiformes and Pleuronectiformes. The cods are characterized by very low level of the enzyme or by the absence of its activity in some...

  • Influence of different rearing systems on natural immune parameters in broiler turkeys. Franciosini, M. P.; Bietta, A.; Moscati, L.; Battistacci, L.; Pela, M.; Tacconi, G.; Davidson, I.; Casagrande Proietti, P. // Poultry Science;Jul2011, Vol. 90 Issue 7, p1462 

    The aim of this study was to determine serological values of lysozyme, hemolytic complement levels (alternative pathway), and bactericidal activity of serum in turkeys kept in different rearing systems (industrial, backyard, and experimental). Results showed that the values for serum...

  • WHAT TO EAT FOR PERFECT SKIN.  // Harper's Bazaar;Nov2009, Issue 3576, p184 

    The article offers tips on the right food to eat to achieve a perfect skin such as controlling caffeine, eating antioxidants and watching sugar intake.

  • HOW FAECAL EGG COUNT IS HELPING OUT. Anderson, Jenny // Farmers Weekly;3/22/2002, Vol. 136 Issue 12, pS18 

    Discusses the use of fecal egg counting (FEC) technique in parasite monitoring in farms in Great Britain. Factors used by producers to deal with worms infections; Aim of FEC tests; Uses of FEC.

  • The Scoop on Moose Poop. Zaidle, Don // Outdoor Life;Feb2000, Vol. 205 Issue 1, p16 

    Deals with a study of moose feces by a group of researchers to evaluate the declining moose population at the Yellowstone National Park.

  • Effects of dextran on lysosomal ultrastructure and protein digestion in renal proximal tubule. Christensen, Erik Ilsø Maunsbach, Arvid B. // Kidney International;Sep1978, Vol. 16 Issue 3, p301 

    The effects of dextran on renal ultrastructure and on the handling of protein by renal proximal tubules were evaluated in dextran-tolerant rats. In vivo and in vitro systems were studied by a combination of electron microscope and cell fractionation techniques. Dextran was demonstrated by...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics