Glutamine deprivation facilitates tumour necrosis factor induced bacterial translocation in Caco-2 cells by depletion of enterocyte fuel substrate
- Eicosanoids and the Gastrointestinal Tract: Promising but No Verdict Yet. Rigas, Basil // American Journal of Gastroenterology;Mar1986, Vol. 81 Issue 3, p218
Discusses the emergence of eicosanoids, an oxygenated derivatives of 20 carbon atoms of long unsaturated fatty acids as treatment for gastrointestinal diseases. Chemical structure of eicosanoids; Mechanism of actions of various eicosanoids; Indication of prostaglandins in peptic ulcer disease.
- Microbiome: Secret behind commensal resilience revealed. Kåhrström, Christina Tobin // Nature Reviews Microbiology;Mar2015, Vol. 13 Issue 3, p127
The article reports that dominant gut phyla are resistant to inflammation-associated antimicrobial peptides (AMPs), referencing the study "Antimicrobial peptide resistance mediates resilience of prominent gut commensals during inflammation," by T. Cullen and colleagues in the "Science" journal.
- Keratinocytes. Vohr, Hans-Werner // Encyclopedic Reference of Immunotoxicology;2005, p365
An entry for "keratinocytes" is presented. These major epidermal cells acts as signal transducers, converting inflammatory mediators.
- MÃ³zg i cytokiny - wspÃ³lne podÅ‚oÅ¼e depresji, otyÅ‚oÅ›ci i chorÃ³b ukÅ‚adu krÄ…zenia? Ufnal, Marcin; Wolynczyk-Gmaj, Dorota // Advances in Hygiene & Experimental Medicine / Postepy Higieny i ;2011, Vol. 65, p228
Accumulating evidence points to a pivotal role of the brain in the regulation of the circulatory system and energy balance. It has also been found that common civilization diseases such as depression, obesity, hypertension, myocardial infarction or heart failure are accompanied by an increase in...
- Polyunsaturated fatty acids support epithelial barrier integrity and reduce IL-4 mediated permeability in vitro. Willemsen, Linette; Koetsier, Marleen; Balvers, Martin; Beermann, Christopher; Stahl, Bernd; Tol, Eric // European Journal of Nutrition;Jun2008, Vol. 47 Issue 4, p183
The intestinal mucosa functions as a barrier against harmful dietary and microbial antigens. An intact gut barrier forms a prerequisite for protection against infection and allergy. Both allergic and inflammatory mediators (e.g. IL-4, IFN-Î³) are known to compromise the epithelial barrier...
- Splanchnic-Brain Crosstalk Mediated By Chemokines In Portal Hypertensive Rats. Merino, Joaquin; Aller, Maria-Angeles; Rubio, Sandra; LosCertales, Maria; Nava, Maria-Paz; Arias, Jaime; Arias, Jorge L. // Internet Journal of Gastroenterology;2008, Vol. 7 Issue 2, p5
In experimental portal hypertension, the inflammatory cerebral-splanchnic axis alterations could be mediated by chemokines. In Wistar rats with partial portal vein ligation, RANTES, CXCR4/SDF-1alpha and CX3CR1/Fractalkine were measured in several brain and gastrointestinal areas. Nestine and...
- The Short-Term Medical Management of Non-Variceal Upper Gastrointestinal Bleeding. Kovacs, Thomas O. G.; Jensen, Dennis M. // Drugs;2008, Vol. 68 Issue 15, p2105
Upper gastrointestinal (UGI) bleeding occurs frequently and results in substantial patient morbidity, mortality and medical expense. After initial resuscitation to stabilize the patient, carefully performed endoscopy provides an accurate diagnosis and can identify high-risk subgroups in ulcer...
- A Case of an Inflammatory Fibroid Polyp of the Cecum. Kan, Hayato; Suzuki, Hideyuki; Shinji, Seiichi; Naito, Zenya; Furukawa, Kiyonori; Tajiri, Takashi // Journal of Nippon Medical School;2008, Vol. 75 Issue 3, p181
An inflammatory fibroid polyp (IFP) is a rare benign lesion, originating in the submucosa of the gastrointestinal tract. It is histopathologically characterized by distinctively arranged fibrous connective tissue and blood vessels with inflammatory cell infiltration. It typically arises in the...
- Gut microbes extend reach to systemic innate immunity. Philpott, Dana J.; Girardin, Stephen E. // Nature Medicine;Feb2010, Vol. 16 Issue 2, p160
The article discusses the study on the influence of bacterial peptidoglycan from the intestinal microflora to the neutrophil function. It is stated that the study found that the peptidoglycan sensor Nod1 detects peptidoglycans and mediates inflammation. It notes that the study found that...