Autoantibodies: Diagnostic fingerprints and etiologic perplexities
- `Anti-Neutrophil Cytoplasmic Autoantibodies.. Falk, R.J.; Jennette, J.C. // New England Journal of Medicine;6/23/88, Vol. 318 Issue 25, p1651
Report of a study titled `Anti-Neutrophil Cytoplasmic Autoantibodies with Specificity for Myeloperoxidase in Patients with Systemic Vasculitis and Idiopathic Necrotizing and Crescentic Glomerulonephoitis.' Details of study; Conclusion that these clinically diverse diseases may have a similar...
- Glomerular binding of anti-dsDNA autoantibodies: The dispute resolved? // Kidney International;Aug2007, Vol. 72 Issue 3, p381
A correction to the article "Glomerular binding of anti-dsDNA autoantibodies: The dispute resolved?" is presented.
- New insights into the pathogenesis of anti-Ro antibody associated congenital complete heart block. Rosenthal, E. // Lupus;1998, Vol. 7 Issue 3, p135
Editorial. Focuses on the anti-Ro antibody pathogenesis. Questions raised on the significance of the antibodies; Impact of autoantibodies on calcium channel currents.
- Street conversations with Henry Kunkel. Elkon, K B // Lupus;2003, Vol. 12 Issue 3, p170
Nineteen eighty two was a fertile time for lupus research on York Avenue. The molecular and functional characteristics of the lupus autoantigens were being discovered by the newly introduced technologies, immunoprecipitation and western blotting. Were the antigens providing the essential clue to...
- islet autoantibodies, islet cell antibodies. // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p1237
A definition of the term "islet autoantibodies, or islet cell antibodies" which refers to antibodies created against insulin, glutamic acid decarboxylase or protein tyrosine phosphatase-like molecules is presented.
- Basophil Phenotypes in Chronic Idiopathic Urticaria in Relation to Disease Activity and Autoantibodies. // Journal of Investigative Dermatology;Jun2009, Vol. 129 Issue 6, p1590
A correction to the article "Basophil Phenotypes in Chronic Idiopathic Urticaria in Relation to Disease Activity and Autoantibodies" is presented.
- A Comprehensive, Statistically Powered Analysis of GAD2 in Type 1 Diabetes. Johnson, Gillian C.L.; Payne, Felicity; Nutland, Sarah; Stevens, Helen; Tuomilehto-Wolf, Eva; Tuomilehto, Jaakko; Todd, John A. // Diabetes;Sep2002, Vol. 51 Issue 9, p2866
GAD2 maps to chromosome 10p11.23 and encodes the 65-kDa isoform of GAD65, a major autoantigen in type 1 diabetes. The genetic variation that influences expression of preproinsulin mRNA, encoding another major autoantigen in type 1 diabetes, has already been shown to be genetically associated...
- New antibody further demarcates chronic, acute urticaria. Campbell, Maude // Dermatology Times;Aug98, Vol. 19 Issue 8, p47
Focuses on a research which shows that a pathogenic, circulating autoantibody was present in patients with chronic urticaria. Practical application of the identification of the autoantibody; Details on three immunotherapies; Significance of the discovery of the circulating autoantibody on...
- Effects of carboxy-terminal modifications of proteinase 3 (PR3) on the recognition by PR3-ANCA. Capizzi, Stephen A.; Viss, Margaret A.; Hummel, Amber M.; Fass, David N.; Specks, Ulrich // Kidney International;Feb2003, Vol. 63 Issue 2, p756
Effects of carboxy-terminal modifications of proteinase 3 (PR3) on the recognition by PR3-ANCA. Background. Autoantibodies directed against neutrophil proteinase 3 (PR3-ANCA) from patients with Wegener's granulomatosis and microscopic polyangiitis recognize conformational epitopes of PR3. During...