TITLE

Increased expression of miRNA-182 in colorectal carcinoma: an independent and tissue-specific prognostic factor

AUTHOR(S)
Shuang Wang; Min-Hui Yang; Xiao-Yan Wang; Jie Lin; Yan-Qing Ding
PUB. DATE
June 2014
SOURCE
International Journal of Clinical & Experimental Pathology;2014, Vol. 7 Issue 6, p3498
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
96961646

 

Related Articles

  • Overexpression of miRNA-21 promotes radiation-resistance of non-small cell lung cancer. Wang Xiao-chun; Wang Wei; Zhang Zhu-Bo; Zhao Jing; Tan Xiao-Gang; Luo Jian-Chao // Radiation Oncology;2013, Vol. 8 Issue 1, p1 

    Background: MiRNA-21 was previously reported to be up-regulated in many kinds of cancer. In the present study, we want to investigate the potential role of miRNA-21 in non-small cell lung cancer. Materials and methods: Expression of miRNA-21 was detected in 60 non-small cell lung cancer (NSCLC)...

  • Establishment and validation of a 7-microRNA prognostic signature for non-small cell lung cancer. Wang, Nan; Guo, Huihui; Dong, Zhaohuo; Chen, Qiuqiang; Zhang, Xilin; Shen, Weiyun; Bao, Ying; Wang, Xiang // Cancer Management & Research;Sep2018, Vol. 10, p3463 

    Purpose: A series of microRNAs (miRNAs) have been identified as associated with the survival of patients with non-small-cell lung cancer (NSCLC). The aim of the present study was to explore whether combination of these experimentally validated individual miRNA biomarkers could be used to further...

  • MicroRNA 135a Suppresses Lymph Node Metastasis through Down-Regulation of ROCK1 in Early Gastric Cancer. Shin, Ji-Young; Kim, Young-Il; Cho, Soo-Jeong; Lee, Mi Kyung; Kook, Myeong-Cherl; Lee, Jun Ho; Lee, Sang Soo; Ashktorab, Hassan; Smoot, Duane T.; Ryu, Keun Won; Kim, Young-Woo; Choi, Il Ju // PLoS ONE;Jan2014, Vol. 9 Issue 1, p1 

    MicroRNAs (miRNAs) play a critical role in gastric cancer progression and metastasis. This study investigated the role of miRNA-135a in early gastric cancer (EGC) including lymph node (LN) metastasis. We examined the correlation between miRNA-135a expression and clinical outcomes in 59 patients...

  • Down-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancer. Pichler, M; Winter, E; Stotz, M; Eberhard, K; Samonigg, H; Lax, S; Hoefler, G // British Journal of Cancer;5/22/2012, Vol. 106 Issue 11, p1826 

    Background:MicroRNA-143 (miRNA-143) is frequently down-regulated in colorectal cancer (CRC) and may influence CRC cell proliferation, apoptosis and sensitivity to 5-fluorouracil. mRNA encoded by the KRAS oncogene has been identified as a target of miRNA-143. However, the prognostic significance...

  • MicroRNA-126 and epidermal growth factor-like domain 7-an angiogenic couple of importance in metastatic colorectal cancer. Results from the Nordic ACT trial. Hansen, T F; Christensen, R dP; Andersen, R F; Sørensen, F B; Johnsson, A; Jakobsen, A // British Journal of Cancer;9/3/2013, Vol. 109 Issue 5, p1243 

    Background:This study investigated the clinical importance of linked angiogenetic biomarkers to chemotherapy, combined with the anti-vascular endothelial growth factor A (anti-VEGF-A), as a first-line treatment in patients with metastatic colorectal cancer (mCRC).Methods:A total of 230 patients...

  • MicroRNA Dysregulations in Gastrointestinal Cancers: Pathophysiological and Clinical Perspectives. Wu, William K. K.; Sung, Joseph J. Y. // Intestinal Research;2012, Vol. 10 Issue 4, p324 

    Two common gastrointestinal cancers, namely, gastric and colorectal cancers, cause high mortality and morbidity. The development of gastrointestinal cancers usually follows stepwise processes with recognizable pre-neoplastic changes. A class of noncoding RNA known as microRNA (miRNA) is...

  • Up-Regulation of MicroRNA-21 Indicates Poor Prognosis and Promotes Cell Proliferation in Esophageal Squamous Cell Carcinoma via Upregulation of lncRNA SNHG1. Luo, Dongbo; Huang, Zhenyi; Lv, Hongbo; Wang, Yang; Sun, Wei; Sun, Xiaohong // Cancer Management & Research;Jan2020, Vol. 12, p1 

    Introduction: MicroRNA-21 (miRNA-21) and lncRNA SNHG1 (small nucleolar RNA host gene 1) are known to be aberrantly upregulated and promote tumor progression in various cancers. Nevertheless, very few studies have determined the roles of tissue and circulating miRNA-21 and SNHG1 in ESCC patients....

  • miR-129 as a novel therapeutic target and biomarker in gastrointestinal cancer. Fesler, Andrew; Haiyan Zhai; Jingfang Ju // OncoTargets & Therapy;Aug2014, Vol. 7, p1481 

    In the last decade, cancer research efforts in the field of noncoding microRNA (miRNA) have been growing exponentially. miRNA-based therapeutics have been tested in both preclinical and clinical settings, and miRNA-based cancer diagnostics and prognostics have moved into clinics to help better...

  • Diagnostic and Prognostic Value of Serum MicroRNA-206 in Patients with Gastric Cancer. Hou, Cheng-Gong; Luo, Xiang-Yu; Li, Gang // Cellular Physiology & Biochemistry (Karger AG);Sep2016, Vol. 39 Issue 4, p1512 

    Aims: Recent studies have demonstrated that microRNAs (miRNAs) can serve as useful biomarkers for human cancers. The aim of this study was to evaluate the expression level of serum miRNA-206 in patients with gastric cancer (GC) and investigate its diagnostic and prognostic value. Methods:...

  • Diet and lifestyle factors associated with miRNA expression in colorectal tissue. Slattery, Martha L.; Herrick, Jennifer S.; Mullany, Lila E.; Stevens, John R.; Wolff, Roger K. // Pharmacogenomics & Personalized Medicine;Jan2017, Vol. 10, p1 

    MicroRNAs (miRNAs) are small non-protein-coding RNA molecules that regulate gene expression. Diet and lifestyle factors have been hypothesized to be involved in the regulation of miRNA expression. In this study it was hypothesized that diet and lifestyle factors are associated with miRNA...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics