TITLE

Systematic review of intravenous immunoglobulin in haemolytic disease of the newborn

AUTHOR(S)
Gottstein, R.; Cooke, R.W.I.
PUB. DATE
January 2003
SOURCE
Archives of Disease in Childhood -- Fetal & Neonatal Edition;Jan2003, Vol. 88 Issue 1, pF6
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objectives: To assess the effectiveness of high dose intravenous immunoglobulin (HDIVIG) in reducing the need for exchange transfusion in neonates with proven haemolytic disease due to Rh and/or ABO incompatibility. To assess the effectiveness of HDIVIG in reducing the duration of phototherapy and hospital stay. Design: Systematic review of randomised and quasi-randomised controlled trials comparing HDIVIG and phototherapy with phototherapy alone in neonates with Rh and/or ABO incompatibility. Results: Significantly fewer infants required exchange transfusion in the HDIVIG group (relative risk (RR) 0.28 (95% confidence interval (CI) 0.17 to 0.47); number needed to treat 2.7 (95% CI 2.0 to 3.8)). Also hospital stay and duration of phototherapy were significantly reduced. Conclusion: HDIVIG is an effective treatment.
ACCESSION #
9694261

 

Related Articles

  • Significance of fetal hemoglobin-containing erythroblasts (F blasts) and the F blast/F cell ratio in myelodysplastic syndromes. Choi, J.W.; Kim, Y. // Leukemia (08876924);Aug2002, Vol. 16 Issue 8, p1478 

    To investigate the relationship between the fetal hemoglobincontaining erythroblasts (F blasts) and apoptosis in myelodysplastic syndromes (MDS), we immunohistochemically assessed F blasts, F cells, and apoptosis in 137 patients with MDS. A marked increase in the number of F blasts in the bone...

  • Chromatin looping and globin expression. Niemitz, Emily // Nature Genetics;Oct2014, Vol. 46 Issue 10, p1050 

    The article discusses the activation of fetal globin expression in mouse and human adult erythroblasts through the process of forced chromatin looping and also reports about the treatment of hemoglobinpathies.

  • X-ray Study of Human Dental Tissues Affected by Erythroblastosis Fetalis. Sui, T.; Ying, S.; Korsunsky, A. M.; Landini, G. // Journal of Dental Research;Jul2015, Vol. 94 Issue 7, p1004 

    Numerous diseases are known to cause microstructural alteration of dental tissues structure. One type in particular is associated with neonatal jaundice and circulation of bilirubin in blood at high concentration due to increased hemolysis in conditions such as erythroblastosis fetalis,...

  • Successfull Perinatal Management of Hydrops Fetalis Due to Hemolytic Disease Associated with D-- -- Maternal Phenotype. Aref, K.; Boctor, F.N.; Pandle, S.; Uehlinger, J.; Manning, F.; Eglowstein, M.; Mallozzi, A.; Bebbington, M.; Weinberg, G.; Rosen, O.; Raab, C.; Brion, L.P. // Journal of Perinatology;Dec2002, Vol. 22 Issue 8, p667 

    Focuses on the successful perinatal management of hydrops fetalis due to hemolytic disease associated with D-- maternal phenotype. Efficacy of intravenous immunoglobulins in treating hemolytic disease of the newborn infant; Serial assessments of fetal ultrasonogram.

  • Fetal Sex and Hemolytic Disease from Maternal Red-Cell Alloimmunization. Ulm, Barbara; Ulm, Martin R.; Panzer, Simon // New England Journal of Medicine;06/04/98, Vol. 338 Issue 23, p1699 

    The article presents a letter to the editor about the relationship between fetal sex and hemolytic disease.

  • "ABO Hemolytic Disease" Smith, David W.; Stevenson, David K. // Clinical Pediatrics;Feb1986, Vol. 25 Issue 2, p116 

    Presents a letter to the editor about newborn screening for ABO hemolytic disease.

  • Rhesus immunisation during pregnancy: the case for antenatal anti-D. Clarke, Cyril; Whitfield, A.G.W. // British Medical Journal;3/29/1980, Vol. 280 Issue 6218, p903 

    Reports the case of infant mortality from rhesus hemolytic disease. Increase in the volume of bilirubin concentration; Detection of anti-D at delivery; Failure of anti-D prophylaxis.

  • Hemolytic disease of the newborn: lowest achievable incidence rates. Hensleigh, Paul A.; Rennie, Drummond; Dan, Bruce B.; Hensleigh, P A // JAMA: Journal of the American Medical Association;11/13/91, Vol. 266 Issue 18, p2562 

    Presents a letter to the editor in response to the article 'Epidemiology of Rh Hemolytic Disease of the Newborn in the U.S.,' by Gilberto F. Chavez et al., in a 1991 issue of the 'Journal of the American Medical Association.'

  • HMO market penetration and hospital cost inflation in California. Robinson, J.C. // JAMA: Journal of the American Medical Association;11/20/91, Vol. 266 Issue 19, p2719 

    Measures the impact of health maintenance organization (HMO) induced price competition on the rate of inflation in average cost per admission for 298 private, non-HMO hospitals between 1982 and 1988. Fee-for-service health insurance plans; Data and methods; Statistical analysis; Growth in HMO...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sign out of this library

Other Topics