Incidence of gallstones in chronic renal failure patients undergoing hemodialysis: experience of a center in Turkey

Altiparmak, Mehmet Riza; Pamuk, Ömer Nuri; Pamuk, G.ülsüm Emel; Çelik, Aykut Ferhat; Apaydın, S.üheyla; Çebi, Deniz; Mihmanlı, Ismail; Erek, Ekrem
April 2003
American Journal of Gastroenterology;Apr2003, Vol. 98 Issue 4, p813
Academic Journal
: ObjectivesIn this case–control study, we sought to determine whether the incidence of gallbladder stones (GBS) was increased in chronic renal failure (CRF) patients on a hemodialysis (HD) program. We also evaluated factors, such as lipid profiles and gallbladder motility, that could affect the formation of GBS. In addition, we reviewed other available studies on this subject and compared the factors that might have some influence on the development of GBS.: MethodsA total of 182 CRF patients (135 male, 47 female, mean age 32.1 yr) undergoing chronic HD and who were referred to our transplantation center in the last 10 yr and 194 healthy controls (137 male, 57 female, mean age 33.3 yr) were included in the study. Abdominal ultrasound was performed on all patients, and ALT, AST, and lipid profiles were determined. In addition, 19 patients with CRF (12 male, 7 female, mean age 33.5 yr) and 22 controls (14 male, 8 female, mean age 33.2 yr) who were age and sex matched were randomly chosen for gallbladder emptying, monitored by ultrasound at 30-min intervals for 2 h after a mixed meal. Fasting volume, minimal residual volume, and ejection fraction of the gallbladder were assessed. For statistical analysis, χ2, t test, and logistic regression analysis were used.: ResultsGBS were detected in seven patients with CRF (3.85%, 5 male, 2 female) and three controls (1.55%, one male, two female) (p > 0.05). The mean follow-up time of CRF patients after diagnosis was 39.3 months (range: 2–168), the mean duration of HD was 21.8 months (range: 1–120). The analysis of seven stones in the CRF group revealed that five were cholesterol-rich stones, and two were mixed (cholesterol and bilirubin) stones. Cholesterol levels were higher in the control group, and triglycerides were higher in the CRF group, but these findings were nonsignificant (p > 0.05). Other biochemical values were not significantly different between the groups. CRF patients with and without GBS were similar in their duration of CRF and HD, age, and other biochemical parameters (p > 0.05). When gallbladder emptying was considered, there was no difference between the two groups in fasting volume, residual volume, and ejection fraction (CRF: 89.7%; controls: 92.3%) of the gallbladders (p > 0.05).: ConclusionsWe detected similar incidences of GBS in CRF patients undergoing HD and healthy controls, and this was comparable to the results of most of the previous studies. Young male CRF patients had a nonsignificantly higher incidence of GBS than control males. Although cholesterol-rich GBS were predominant, we could not find any significant difference between the groups when factors that could affect GBS formation, such as lipid profiles and gallbladder motility, were taken into account.


Related Articles

  • Gallbladder mucocele in a dog: an ultrasonography and pathology report. THANGAPANDIYAN, Marudhai; SRIDHAR, Ramasamy; JEYARAJA, Kirubakaran; SAKTHIVELAN, Masilamani; MOHANAPRIYA, Ihangaraj; PAZHANIVEL, Natesan // Turkish Journal of Veterinary & Animal Sciences;2014, Vol. 38 Issue 4, p459 

    A 9-year old male, German shepherd dog was presented to the Madras Veterinary College Teaching Hospital with a history of a chronic ailment that had increased over the previous few months. A diagnosis of chronic renal failure and hepatitis was made and abdominal ultrasonography revealed the...

  • Sevoflurane Anaesthesia in a Patient with Renal Transplantation: Case Report and Literature Review. Eroglu, Ahmet; Erturk, Engin; Bostan, Habib // Internet Journal of Anesthesiology;2007, Vol. 13 Issue 1, p30 

    In this case report, we have presented our anaesthetic management in a patient undergoing urgent abdominal surgery who has undergone renal transplantation before, and has been in a chronic haemodialysis program two times a week. Anaesthesia was induced with sevoflurane in nitrous oxide-oxygen...

  • Laparoscopic cholecystectomy for 58 end stage renal disease patients. Yeh, C.-N.; Chen, M.-F.; Jan, Y.-Y. // Surgical Endoscopy;Jul2005, Vol. 19 Issue 7, p915 

    Background: Since 1987, laparoscopic cholecystectomy (LC) has been widely used as the favored treatment for gallbladder lesions throughout the world. Because hemorrhage, infection, and delayed wound healing are the main causes of death after surgery for end-stage renal disease...

  • Small cell cervical cancer: an unusual finding at cholecystectomy. Boyle, Emily; Nzewi, Emeka; Khan, Iqbal; Al-Akash, Musallam; Crotty, Paul; Neary, Paul // Archives of Gynecology & Obstetrics;Feb2009, Vol. 279 Issue 2, p251 

    Small cell carcinoma of the cervix is a rare cancer, comprising less than 3% of all cervical neoplasms. It uniformly has a poor prognosis, and has a high mortality even with early stage disease. It can metastasise rapidly and metastatic sites include lung, liver, brain, bone, pancreas and lymph...

  • Symptoms and Pregnancy Outcomes Associated with Extreme Weight Loss among Women with Hyperemesis Gravidarum. Fejzo, Marlena S.; Poursharif, Borzouyeh; Korst, Lisa M.; Munch, Shari; MacGibbon, Kimber W.; Romero, Roberto; Goodwin, T. Murphy // Journal of Women's Health (15409996);Dec2009, Vol. 18 Issue 12, p1981 

    Objective: To report the weight loss and associated symptoms experienced by a large cohort of women with hyperemesis gravidarum (HG). Methods: Data were obtained from an HG website registry, where women with HG were recruited on-line. Respondents were included if they experienced at least 1 live...

  • Bacterium Causes Gastroesophageal Junction Inflammation and Exposes Uncontrolled Diabetes and Other Infections in an Adult Male. Redwine, Gerald D.; FACG, W. Kern Deschner; John Lee Sang // Laboratory Medicine;Spring2013, Vol. 44 Issue 2, p151 

    Patient: 52-year-old African-American male. Chief Complaint: Severe abdominal pain and difficulty eating. History of Present Illness: The patient presented to the emergency room (ER) with severe abdominal pain. Approximately 3 months prior to his visit, the patient stopped taking his metformin...

  • Erthyropoietin Stops Chronic Diffuse Transfusion-Dependent Gastrointestinal Bleeding. Zaharia-Czeizler, Veronica // Annals of Internal Medicine;11/20/2001, Vol. 135 Issue 10, p933 

    Examines the benefits of erythropoietin in anemic patient with chronic renal failure. Decline in the bleeding time in uremic patients; Increase in the platelet count; Decrease in protein C, protein S and antithrombin III levels.

  • CKDu Ravages the Salvadoran Countryside. Gorry, Conner // MEDICC Review;Apr2014, Vol. 16 Issue 2, p5 

    This article focuses on the prevalence of chronic kidney disease (CKD) of unknown etiology among poor farmworkers in El Salvador. Topics discussed include the extent and nature of the problem, the risk factors for CKD, and the response of the Ministry of Health and the Salvadoran government to...

  • HOOFING IT HEALTHY FOR KIDNEY PATIENTS' HEARTS.  // Canadian Nurse;May2014, Vol. 110 Issue 4, p8 

    The article discusses a study of 40 patients with chronic kidney disease where immune cell activation and markers of systematic inflammation were reduced among patients who added a 30-minute walk to their daily routine.


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics