TITLE

Epstein-Barr Virus and Human Herpesvirus 8 Coinfection and Concomitant Extranodal Nasal-Type NK/T Cell Lymphoma and Castleman Disease: Case Report

AUTHOR(S)
Larroche, Claire; Agbalika, Félix; Poirel, Hélène; Martin, Antoine; Gautheret-Dejean, Agnès; Raphaël, Martine; Lortholary, Olivier
PUB. DATE
May 2003
SOURCE
Clinical Infectious Diseases;5/1/2003, Vol. 36 Issue 9, pe107
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
We describe a 36-year-old man uninfected with human immunodeficiency virus who had confirmed concurrent infection with Epstein-Barr virus (EBV) and human herpesvirus 8 (HHV-8) and their respective lymphoproliferative manifestations, nasal-type NK/T cell lymphoma and Castleman disease. Antibodies to HHV-8 and EBV DNA were found in plasma and peripheral blood mononuclear cells. An EBV-positive nasal-type NK/T cell lymphoma infiltrated the splenic red pulp, whereas the white pulp contained HHV-8-positive plasmablasts, as found in Castleman disease.
ACCESSION #
9632494

 

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