TITLE

Phenolic Metaboloites and Antioxidant Activity of Codiaeum variegatum CV. spirale

AUTHOR(S)
Hassan, Emad M.; Hassan, Rasmia A.; El-Toumy, Sayed A.; Mohamed, Samy M.; Omer, Elsayed A.
PUB. DATE
May 2014
SOURCE
Journal of Pharmacy Research;May2014, Vol. 8 Issue 5, p619
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The methanol extract of Codiaeum variegatum cv. spirale yielded five flavonoids; apigenin, orientin, vitexin, isovitexin and vicenin-2 along with phenolic acids known as caffeic and ρ-coumaric acids. Structures of the isolated compounds were determined by using chromatography, MS and 1H, 13C NMR spectroscopy. The antioxidant activity of the main isolated compounds; apigenin, vitexin and isovitexin was investigated using the DPPH, total reduction capability and inhibition of lipid peroxidation assay. Vitexin exhibited the highest DPPH radical scavenging antioxidant activity (IC50 = 8.95 μg ml-1). In addition, vitexin and isovitexin showed a significant reducing power (RP50 = 8.65 and 9.27 μg ml-1, respectively). While, apigenin was found to be the active compound against the lipid peroxidation process (IC50 = 31.82 μg ml-1).
ACCESSION #
96265170

 

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