Patient With iDEND Syndrome--Related Mutation

Prado-Carro, Ana M.; Calzada-Hernández, Joan; Marín, Silvia; Cardona-Hernandez, Roque; Oriola, Josep; Nicolás, Marta; Ramon-Krauel, Marta
June 2014
Diabetes Care;Jun2014, Vol. 37 Issue 6, pe123
Academic Journal
The article focuses on the improvement of metabolic control and neurologic outcome for neonatal patients based on the result of genetic confirmation of a sulfonylurea-responsive form of diabetes. Topics include the role of mutations on the ATP-sensitive K+ (KATP) in diabetes, the effect of sulfonylureas on KATPchannel function and the use of glyburide in neonatal patients. The case of neonatal diabetes treated with sulfonylureas is presented.


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