Effect of space flight factors simulated in ground-based experiments on the behavior, discriminant learning, and exchange of monoamines in different brain structures of rats

Shtemberg, A.; Lebedeva-Georgievskaya, K.; Matveeva, M.; Kudrin, V.; Narkevich, V.; Klodt, P.; Bazyan, A.
April 2014
Biology Bulletin;Apr2014, Vol. 41 Issue 2, p161
Academic Journal
Experimental treatment (long-term fractionated γ-irradiation, antiorthostatic hypodynamia, and the combination of these factors) simulating the effect of space flight in ground-based experiments rapidly restored the motor and orienting-investigative activity of animals (rats) in 'open-field' tests. The study of the dynamics of discriminant learning of rats of experimental groups did not show significant differences from the control animals. It was found that the minor effect of these factors on the cognitive performance of animals correlated with slight changes in the concentration of monoamines in the brain structures responsible for the cognitive, emotional, and motivational functions.


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