TITLE

Genetic instability and tumor cell variation: Implications for immunotherapy

AUTHOR(S)
Fenton, Robert G.; Longo, Dan L.
PUB. DATE
February 1995
SOURCE
JNCI: Journal of the National Cancer Institute;2/15/95, Vol. 87 Issue 4, p241
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Discusses the implications of immunotherapy in genetic instability and tumor cell variation. Nature of cancer as a genetic disease; Efficacy of immunotherapy in cancer treatment; Difficulty in inducing antitumor responses; Observing I MHC allospecificities in tumor histologies; Tumor escape mechanisms in formulating effective immunotherapy approaches; Activation of multiple effector pathways.
ACCESSION #
9502271744

 

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