TITLE

PROSTATE CANCER DIAGNOSTICS WITH BIOPSY MATERIAL

AUTHOR(S)
Fedorina, T. A.; Poletaeva, S. V.
PUB. DATE
October 2013
SOURCE
Saratov Journal of Medical Scientific Research / Saratovskii Nau;Oct-Dec2013, Vol. 9 Issue 4, p632
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The aim of the article is to study the potential importance of specific location of biopsy of prostate cancer. Material and methods. Histological material from 700 patients has been examinated. 580 specimen of radical prostatectomy were examined. TRUS-guided 12-cores biopsy has been performed in all patients. Histological, computer morphomet-ric, immunohistochemal methods (PIN4-coctail, AR) were used. Results. It has been established that undergrading of carcinoma in needle biopsy occurred in 26% of patients. Overgrading of carcinoma in needle biopsy may also occur, but it was only found in 3% of cases. Undergrading results have been explained by low amount of tumor elements taken from tiny areas of carcinoma, multicentric growth and heterogenous structure of tumor. Conclusions. An important task is to identify the minimal or limited adenocarcinoma in biopsies, as tumor of >1cc volume is often found in prostatectomy specimen.
ACCESSION #
94929463

 

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