The Effects of Anti-infective Preventive Measures on the Occurrence of Biologic Implant Complications and Implant Loss: A Systematic Review

Salvi, Giovanni E.; Zitzmann, Nicola U.
January 2014
International Journal of Oral & Maxillofacial Implants;2014 Supplement, Vol. 29, p292
Academic Journal
Purpose: To systematically appraise whether anti-infective protocols are effective in preventing biologic implant complications and implant loss after a mean observation period ≥ 10 years after loading. Materials and Methods: An electronic search of Medline via PubMed and Embase via Ovid databases complemented by manual search was conducted up to October 31, 2012. Studies were included provided that they were published in English, German, French, or Italian, and conducted on ≥ 20 partially and fully edentulous patients with dental implants and regular (≥ 1×/year) supportive periodontal therapy (SPT) over a mean observation period ≥ 10 years. Assessment of the identified studies and data extraction were performed independently by two reviewers. Authors were contacted if required. Collected data were reported by descriptive methods. Results: The initial electronic search resulted in the identification of 994 titles from Medline via PubMed and 531 titles from Embase via Ovid databases, respectively. After elimination of duplicate titles and exclusion of 60 full-text articles, 143 articles were analyzed, resulting in 15 studies eligible for qualitative analysis. The implant survival rate ranged from 85.7% to 99.2% after a mean observation period ≥ 10 years. One comparative study assessed the effects of regular SPT on the occurrence of biologic complications and implant loss. Overall, regular diagnosis and implementation of anti-infective therapeutic protocols were effective in the management of biological complications and prevention of implant loss. Residual probing depths at the end of active periodontal therapy and development of reinfection during supportive periodontal therapy (SPT) represented a significant risk for the onset of peri-implantitis and implant loss. Comparative studies indicated that implant survival and success rates were lower in periodontally compromised vs noncompromised patients. Conclusions: In order to achieve high long-term survival and success rates of dental implants and their restorations, enrollment in regular SPT including anti-infective preventive measures should be implemented. Therapy of peri-implant mucositis should be considered as a preventive measure for the onset of peri-implantitis. Completion of active periodontal therapy should precede implant placement in periodontally compromised patients.


Related Articles

  • The Therapy of Peri-implantitis: A Systematic Review. Heitz-Mayfield, Lisa J. A.; Mombelli, Andrea // International Journal of Oral & Maxillofacial Implants;2014 Supplement, Vol. 29, p325 

    Purpose: To evaluate the success of treatments aimed at the resolution of peri-implantitis in patients with osseointegrated implants. Materials and Methods: The potentially relevant literature was assessed independently by two reviewers to identify case series and comparative studies describing...

  • Molecular Assessment of Osseointegration In Vivo: A Review of the Current Literature. Thalji, Ghadeer; Cooper, Lyndon F. // International Journal of Oral & Maxillofacial Implants;2013, Vol. 28 Issue 6, pe521 

    This article examines the results of a structured review of the literature on in vivo molecular assessment of osseointegrated endosseous dental implants. It discusses the methods used in the study, in vivo models used, characteristics of the included in vivo reports and results of a genome-wide...

  • Accuracy of clinical tests in the diagnosis of anterior cruciate ligament injury: a systematic review. Swain, Michael S.; Henschke, Nicholas; Kamper, Steven J.; Downie, Aron S.; Koes, Bart W.; Maher, Chris G. // Chiropractic & Manual Therapies;2014, Vol. 22 Issue 1, p1 

    Background Numerous clinical tests are used in the diagnosis of anterior cruciate ligament (ACL) injury but their accuracy is unclear. The purpose of this study is to evaluate the diagnostic accuracy of clinical tests for the diagnosis of ACL injury. Methods Study Design: Systematic review. The...

  • Is puberty a risk factor for back pain in the young? A systematic critical literature review. Lardon, Arnaud; Leboeuf-Yde, Charlotte; Le Scanff, Christine; Wedderkopp, Niels // Chiropractic & Manual Therapies;2014, Vol. 22 Issue 1, p1 

    Background Back pain is a common condition that starts early in life and seems to increase markedly during puberty. A systematic review was performed in order to investigate the link between puberty and back pain, using some Bradford Hill criteria for causality. Objectives We sought to obtain...

  • Antibiotic Prescribing in Long-Term Care Facilities: A Meta-synthesis of Qualitative Research. Fleming, Aoife; Bradley, Colin; Cullinan, Shane; Byrne, Stephen // Drugs & Aging;Apr2015, Vol. 32 Issue 4, p295 

    Objectives: The objective of this review was to synthesize the findings of qualitative studies investigating the factors influencing antibiotic prescribing in long-term care facilities (LTCFs). These findings will inform the development of future antimicrobial stewardship strategies (AMS) in...

  • Chronic adverse effects of long-term exposure of children to dichlorodiphenyltrichloroethane (DDT) through indoor residual spraying. Osunkentan, AO; Evans, D. // Rural & Remote Health;2015, Vol. 15 Issue 2, p1 

    Introduction: Malaria remains a significant public health problem in endemic regions of the world, most especially in sub-Saharan Africa. As part of the global efforts to control malaria, dichlorodiphenyltrichloroethane (DDT), a cheap and effective chemical, was endorsed by the World Health...

  • Socioeconomic position and incidence of gastric cancer: a systematic review and meta-analysis. Uthman, Olalekan A.; Jadidi, Elham; Moradi, Tahereh // Journal of Epidemiology & Community Health;Oct2013, Vol. 67 Issue 10, p854 

    Background Low socioeconomic position (SEP) has been associated with increased risks of morbidity and mortality from many diseases. We investigated the associations between gastric cancer incidence and education, occupation and income as indicators for SEP. Methods We searched the PubMed and...

  • Factors affecting children's adherence to regular dental attendance. Badri, Parvaneh; Saltaji, Humam; Flores-Mir, Carlos; Amin, Maryam // Journal of the American Dental Association (JADA);Aug2014, Vol. 145 Issue 8, p817 

    Background. Parents’ adherence to regular dental attendance for their young children plays an important role in improving and maintaining children's oral health. The authors conducted a systematic review to determine the factors that influence parental adherence to regular dental...

  • Changes in sedentary behaviours across the retirement transition: a systematic review. SPROD, JUDY; FERRAR, KATIA; OLDS, TIMOTHY; MAHER, CAROL // Age & Ageing;Nov2015, Vol. 44 Issue 6, p918 

    Background: prolonged sedentary behaviour has been associated with a number of chronic health conditions. This issue is compounded by inactivity increasing with age. Objective: this systematic review aimed to identify evidence regarding changes in sedentary behaviours as people move into...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics