TITLE

Cyclin D1 splice site variant triggers chromosomal aberrations in healthy humans

AUTHOR(S)
Hemminki, K; Musak, L; Vymetalkova, V; Smerhovsky, Z; Halasova, E; Osina, O; Letkova, L; Försti, A; Vodickova, L; Buchancova, J; Vodicka, P
PUB. DATE
March 2014
SOURCE
Leukemia (08876924);Mar2014, Vol. 28 Issue 3, p721
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents a research study on the translocation of cyclin D1 (CCND1) G870A genotype in multiple myeloma. Odds ratios (ORs) from multivariable linear regression analysis were used to consider impacts of smoking habits. gender and occupational exposures on the frequencies of chromosome-type aberrations (CSAs), chromatid-type aberrations (CTAs) and chromosomal aberrations (CAs). The results for total CAs revealed significant impacts of CCND1 AA genotype and occupational exposure.
ACCESSION #
94762965

 

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