High prevalence of oncogenic MYD88 and CD79B mutations in primary testicular diffuse large B-cell lymphoma

Kraan, W; van Keimpema, M; Horlings, H M; Schilder-Tol, E J M; Oud, M E C M; Noorduyn, L A; Kluin, P M; Kersten, M J; Spaargaren, M; Pals, S T
March 2014
Leukemia (08876924);Mar2014, Vol. 28 Issue 3, p719
Academic Journal
The article presents a study which examined the role of deregulated MYD88 signaling in primary testicular lymphomas (PTLs). The study material composed a panel of 37 PTL being diagnosed as diffuse large B-cell lymphoma (DLBCL) according to the classification of the World Health Organization. The study revealed that 25 tumors were discovered to harbor a MYD88 mutation of the studied 37 PTLs.


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