TITLE

Comparison of the clinical outcomes of laparoscopic-assisted versus open surgery for colorectal cancer

AUTHOR(S)
KAI CHEN; ZHUQING ZHANG; YUNFEI ZUO; SHUANGYI REN
PUB. DATE
April 2014
SOURCE
Oncology Letters;2014, Vol. 7 Issue 4, p1213
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The present study aimed to compare the clinical outcomes of laparoscopic-assisted surgery versus open surgery for colorectal cancer and investigate the oncological safety and potential advantages and disadvantages of laparoscopic-assisted surgery for colorectal cancer. The medical records from a total of 160 patients who underwent surgery for colorectal cancer between January 2009 and January 2013 at The Second Hospital of Dalian Medical University (Dalian, China) were retrospectively analyzed. The patients who underwent laparoscopic-assisted surgery showed significant advantages due to the minimally invasive nature of the surgery compared with those who underwent open surgery, namely, less blood loss (P=0.002), shorter time to flatus (P<0.001), bowel movement (P=0.009) and liquid diet intake (P=0.015), earlier ambulation time (P=0.006), smaller length of incision (P<0.001) and a shorter post-operative hospital stay (P=0.007). However, laparoscopic-assisted surgery for colorectal cancer resulted in a longer operative time (P=0.015) and higher surgery expenditure (P=0.003) and total hospitalization costs (P<0.001) compared with open surgery. There were no statistically significant differences between the intraoperative and post-operative complications. There were no differences in the local recurrence (P=0.699) or distant metastasis (P=0.699) rates. In addition, no differences were found in overall survival (P=0.894) and disease-free survival (P=0.701). These findings indicated that laparoscopic-assisted surgery for colorectal cancer had the clear advantages of a minimally invasive surgery and relative disadvantages, including a longer surgery time and higher cost, and exhibited similar rates of recurrence and survival compared with open surgery.
ACCESSION #
94754596

 

Related Articles

  • Laparoscopic colectomy for transverse colon carcinoma. Zmora, O.; Bar-Dayan, A.; Khaikin, M.; Lebeydev, A.; Shabtai, M.; Ayalon, A.; Rosin, D. // Techniques in Coloproctology;Mar2010, Vol. 14 Issue 1, p25 

    Laparoscopic resection of transverse colon carcinoma is technically demanding and was excluded from most of the large trials of laparoscopic colectomy. The aim of this study was to assess the safety, feasibility, and outcome of laparoscopic resection of carcinoma of the transverse colon. A...

  • Impact of Minimally Invasive Techniques in Colorectal Surgery. Young-Fadok, Tonia // World Journal of Surgery;Jul2011, Vol. 35 Issue 7, p1505 

    Minimally invasive techniques have had a marked impact on colorectal surgery despite the limited adoption of such techniques. Patients stay in the hospital a shorter time, experience less pain, and have less chance of developing a wound infection, an incisional hernia, a bowel obstruction, or...

  • Laparoscopic Complete Mesocolic Excision via Reduced Port Surgery for Treatment of Colon Cancer. Mori, Shinichiro; Kita, Yoshiaki; Baba, Kenji; Yanagi, Masayuki; Okumura, Hiroshi; Natsugoe, Shoji // Digestive Surgery;Mar2015, Vol. 32 Issue 1, p45 

    Background: Laparoscopic colectomy has become accepted for resection of colon cancer, and laparoscopic complete mesocolic excision (CME) has proved feasible and safe. We have evaluated the safety, efficacy, and feasibility of laparoscopic CME via reduced port surgery (RPS) in patients with colon...

  • Laparoscopic Colorectomy for Colorectal Cancer: Retrospective Analysis of 889 Patients in a Single Center. Liesheng Lu; Donglei Zhou; Xun Jian; Jianzhong Deng; Ping Yang; Weixing Ding // Tohoku Journal of Experimental Medicine;Jul2012, Vol. 227 Issue 3, p171 

    Laparoscopic colectomy has been reported as an alternative for treatment of colorectal cancer. However, its long-term efficacy and safety remain obscure. The purpose here was to review our experience with laparoscopic colectomy in 899 patients between June 2001 and December 2008. Of them, 43...

  • Cardiac arrest associated with carbon dioxide gas embolism during laparoscopic surgery for colorectal cancer and liver metastasis. Kim, Il-Seok; Jung, Jae-Woo; Shin, Keun-Man // Korean Journal of Anesthesiology;Nov2012, Vol. 63 Issue 5, p469 

    Clinically apparent carbon dioxide (CO2) gas embolism is uncommon, but it may be a potentially lethal complication if it occurs. We describe a 40-year-old woman who suffered a CO2 gas embolism with cardiac arrest during laparoscopic surgery for colorectal cancer and liver metastasis....

  • Intraoperative adverse events during laparoscopic colorectal resection-better laparoscopic treatment but unchanged incidence. Lessons learnt from a Swiss multi-institutional analysis of 3,928 patients. Kambakamba, P.; Dindo, D.; Nocito, A.; Clavien, P.; Seifert, B.; Schäfer, M.; Hahnloser, D. // Langenbeck's Archives of Surgery;Mar2014, Vol. 399 Issue 3, p297 

    Purpose: Intraoperative adverse events significantly influence morbidity and mortality of laparoscopic colorectal resections. Over an 11-year period, the changes of occurrence of such intraoperative adverse events were assessed in this study. Methods: Analysis of 3,928 patients undergoing...

  • Retrospective analysis of the effect of postoperative analgesia on survival in patients after laparoscopic resection of colorectal cancer. Day, A.; Smith, R.; Jourdan, I.; Fawcett, W.; Scott, M.; Rockall, T. // BJA: The British Journal of Anaesthesia;Aug2012, Vol. 109 Issue 2, p185 

    Background Surgical excision of colorectal cancer can reduce immune function during the postoperative period, which may affect long-term survival. There is evidence that regional analgesia may attenuate the immunosuppressive effect of surgery. Opioid analgesia also suppresses cell-mediated...

  • Effects of obesity on the outcome of laparoscopic surgery for colorectal cancer. Miyamoto, Yuji; Ishii, Toshimasa; Tashiro, Jo; Satoh, Takahiro; Watanabe, Masayuki; Baba, Hideo; Yamaguchi, Shigeki // Surgery Today;Jul2014, Vol. 44 Issue 7, p1293 

    Purpose: This study evaluated the feasibility and safety of laparoscopic colorectal surgery for cancer in obese patients based on the short-term outcomes. Methods: We conducted a retrospective analysis of 561 patients with colorectal cancer treated from April 2007 to October 2010. The surgical...

  • Short- and long-term results of laparoscopic surgery for transverse colon cancer. Hirasaki, Yoshinori; Fukunaga, Masaki; Sugano, Masahiko; Nagakari, Kunihiko; Yoshikawa, Seiitirou; Ouchi, Masakazu // Surgery Today;Jul2014, Vol. 44 Issue 7, p1266 

    Purposes: We investigated the feasibility of laparoscopic surgery for transverse colon cancer (TCC) by examining the results of this procedure, and comparing the short- and long-term outcomes with those for right-sided and sigmoid colon cancer (OSCC). Methods: The subjects consisted of 117...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics