Association between multiple sclerosis risk-associated SNPs and relapse and disability – a prospective cohort study

Lin, Rui; Taylor, Bruce V; Simpson, Steve; Charlesworth, Jac; Ponsonby, Anne-Louise; Pittas, Fotini; Dwyer, Terry; van der Mei, Ingrid
March 2014
Multiple Sclerosis Journal;Mar2014, Vol. 20 Issue 3, p313
Academic Journal
The article presents a prospective cohort study which investigates the association between multiple sclerosis (MS) risk-associated single-nucleotide polymorphisms (SNPs) and relapse and disability. Details about the methods of the study are given. The study suggests an association between MS risk-associated SNPs and relapse, with gene-environment interactions an important mechanism of MS clinical course.


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