Risk Factors for Hepatitis C Transmission in HIV Patients, Hepacam Study, ANRS 12267 Cambodia

Goyet, Sophie; Lerolle, Nathalie; Fournier-Nicolle, Isabelle; Ken, Sreymom; Nouhin, Janin; Sowath, Ly; Barennes, Hubert; Hak, Chanroeurn; Ung, Chakravuth; Viretto, Gérald; Delfraissy, Jean-François; Khuon, Pichit; Segeral, Olivier
March 2014
AIDS & Behavior;Mar2014, Vol. 18 Issue 3, p495
Academic Journal
In 2009, we conducted a case-control study to explore the routes of HCV transmission in people living with HIV/AIDS (PLHIV) in Cambodia. Cases were HCV/HIV co-infected patients (who tested RT-PCR positive for HCV-RNA or had confirmed presence of HCV antibodies) (n = 44). Controls were HIV mono-infected patients, with no HCV antibodies (n = 160). They were recruited among the PLHIV presenting at one national reference centre of HIV/AIDS. Multivariate analysis showed that factors associated with the co-infection were the age older than 50 years (OR 5.4, 95 % confidence interval (CI) 1.5-19.6), the exposure to multiple parenteral infusions before the year 2000 (OR 3.4, 95 % CI 1.5-7.6), to surgery (OR 2.6, 95 % CI 1.2-5.7) and to fibroscopy (OR 2.4, 95 % CI 1.0-5.7). These results show the need to implement HCV screening in PLHIV, to support the implementation of national infection control guidelines, and to reinforce public awareness on the risks linked to parenteral medications.


Related Articles

  • Risk factors for pseudogout in the general population. Rho, Young Hee; Zhu, Yanyan; Zhang, Yuqing; Reginato, Anthony M.; Choi, Hyon K. // Rheumatology;Nov2012, Vol. 51 Issue 11, p2070 

    Objective. To evaluate the association between the purported risk factors for chondrocalcinosis and gout and the risk of pseudogout in the general population.Methods. We conducted a case–control study nested within a UK general practice database (The Health Improvement Network) by...

  • Outbreak of Cryptosporidiosis Associated With a Man-Made Chlorinated Lake--Tarrant County, Texas, 2008. Cantey, Paul T.; Kurian, Anita K.; Jefferson, David; Moerbe, Micky M.; Marshall, Karen; Blankenship, William R.; Rothbarth, Gary R.; Hwang, Jimee; Hall, Rebecca; Yoder, Jonathan; Brunkard, Joan; Johnston, Stephanie; Xiao, Lihua; Hill, Vincent R.; Sarisky, John; Zarate-Bermudez, Max A.; Otto, Charles; Hlavsa, Michele C. // Journal of Environmental Health;Nov2012, Vol. 75 Issue 4, p14 

    In July 2008, clusters of laboratory-confirmed cryptosporidiosis cases and reports of gastrointestinal illness in persons who visited a lake were reported to Tarrant County Public Health. In response, epidemiologic, laboratory, and environmental health investigations were initiated. A matched...

  • Parental Age and Risk of Autism Spectrum Disorders in a Finnish National Birth Cohort. Lampi, Katja; Hinkka-Yli-Salomäki, Susanna; Lehti, Venla; Helenius, Hans; Gissler, Mika; Brown, Alan; Sourander, Andre // Journal of Autism & Developmental Disorders;Nov2013, Vol. 43 Issue 11, p2526 

    Aim of the study was to examine the associations between parental age and autism spectrum disorders (ASD). Data were based on the FIPS-A (Finnish Prenatal Study of Autism and Autism Spectrum Disorders), a case-control study with a total of 4,713 cases with childhood autism (n = 1,132),...

  • Opium Could Be Considered an Independent Risk Factor for Lung Cancer: A Case-Control Study. Masjedi, Mohammad Reza; Naghan, Parisa Adimi; Taslimi, Shervin; Yousefifard, Mahmoud; Ebrahimi, Seyyed Meisam; Khosravi, Adnan; Karimi, Shirin; Hosseini, Mostafa; Mortaz, Esmaeil // Respiration;2013, Vol. 85 Issue 2, p112 

    Background: Lung cancer is the leading cause of cancer-related death worldwide, and half of all incident lung cancers are believed to occur in the developing countries, including Iran. Objective: We investigated the association of opium with the risk of lung cancer in a case-control study....

  • Maternal and Paternal Age are Jointly Associated with Childhood Autism in Jamaica. Rahbar, Mohammad; Samms-Vaughan, Maureen; Loveland, Katherine; Pearson, Deborah; Bressler, Jan; Chen, Zhongxue; Ardjomand-Hessabi, Manouchehr; Shakespeare-Pellington, Sydonnie; Grove, Megan; Beecher, Compton; Bloom, Kari; Boerwinkle, Eric // Journal of Autism & Developmental Disorders;Sep2012, Vol. 42 Issue 9, p1928 

    Several studies have reported maternal and paternal age as risk factors for having a child with Autism Spectrum Disorder (ASD), yet the results remain inconsistent. We used data for 68 age- and sex-matched case-control pairs collected from Jamaica. Using Multivariate General Linear Models (MGLM)...

  • Active commuting reduces the risk of wrist fractures in middle-aged women-the UFO study. Englund, U.; Nordström, P.; Nilsson, J.; Hallmans, G.; Svensson, O.; Bergström, U.; Pettersson-Kymmer, U. // Osteoporosis International;Feb2013, Vol. 24 Issue 2, p533 

    Summary: Middle-aged women with active commuting had significantly lower risk for wrist fracture than women commuting by car/bus. Introduction: Our purpose was to investigate whether a physically active lifestyle in middle-aged women was associated with a reduced risk of later sustaining a...

  • Association of Khat and alcohol use with HIV infection and age at first sexual initiation among youths visiting HIV testing and counseling centers in Gamo-Gofa Zone, South West Ethiopia. Tilahun Malaju, Marelign; Ayele Asale, Gistane // BMC International Health & Human Rights;2013, Vol. 13 Issue 1, p10 

    Background: HIV/AIDS is the major problem and an obstacle to both the health and development of people in Ethiopia today. It is also indicated that the use of substances have dramatically increased despite the serious concern about HIV infection. Methods: Unmatched case control study was...

  • Epidemiology of Alcoholic Liver Disease in Denmark 2006-2011: A Population-Based Study. Deleuran, Thomas; Vilstrup, Hendrik; Becker, Ulrik; Jepsen, Peter // Alcohol & Alcoholism;May\Jun2015, Vol. 50 Issue 3, p352 

    Aims: To describe incidence, prevalence, hospitalization rates and survival for alcoholic liver disease (ALD) in Denmark 2006-2011. Methods: Using nationwide healthcare registries we identified all Danish residents with a hospital diagnosis of ALD and computed standardized incidence, prevalence,...

  • Causes of death among Danish HIV patients compared with population controls in the period 1995-2008. Helleberg, M.; Kronborg, G.; Larsen, C.; Pedersen, G.; Pedersen, C.; Gerstoft, J.; Obel, N. // Infection;Dec2012, Vol. 40 Issue 6, p627 

    Purpose: To compare the mortality and causes of death in human immunodeficiency syndrome (HIV) patients with the background population. Methods: All adult HIV patients treated in Danish HIV centers from 1995 to 2008 and 14 controls for each HIV patient were included. Age-adjusted mortality rates...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics