TITLE

Evaluation of Bioactive Potential of Basidiocarp Extracts of Ganoderma lucidum

AUTHOR(S)
Gowrie, S. Uma; Chathurdevi, G.; Rani, K.
PUB. DATE
March 2014
SOURCE
International Journal of Pharmaceutical Research & Allied Scienc;2014, Vol. 3 Issue 1, p36
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The present study was carried out to evaluate antimicrobial potential of Ganoderma lucidum using various concentrations of chloroform extract of basidiocarp against the pathogenic Bacteria (Salmonella typhi, Baicllus subtilis, Escheriachia coli, Klebsiella pneumoniae, Pseudomonas aerunginosa) and Fungi (Aspergillus niger, Aspergillus flavus, Candida albicans, Curvularia species and Fusarium oxysporum). The study revealed that the chloroform extract of basidiocarp of G.lucidum showed antibacterial activity against S.typhi (18mm at 100μl concentration) and antifungal activity against C.albicans (17mm at 100μl concentration). Preliminary phytochemical screening of Ganoderma lucidum was carried out for different extracts to detect the bioactive principles which can help in drug discovery and development. FT-IR analysis of the sample G.lucidum was also carried out to study the distribution of functional group within organic fractions. TLC and HPLC study confirmed the presence of triterpenoids and polysaccharides. Antioxidant activity of Ganoderma lucidum was also assayed.
ACCESSION #
94733740

 

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