Profile, Bacteriology, and Risk Factors for Foot Ulcers among Diabetics in a Tertiary Hospital in Calabar, Nigeria

Otu, Akaninyene Asuquo; Umoh, Victor Aniedi; Essien, Okon Ekwere; Enang, Ofem Egbe; Okpa, Henry Ohem; Mbu, Patrick Ntui
January 2013
Ulcers;2013, p1
Academic Journal
Diabetic foot disease is a major medical, social, and economic problem. This retrospective study assessed the profile of diabetes mellitus patients with foot ulcers in theUniversity of Calabar Teaching Hospital (UCTH), Nigeria. Admission records of all patients admitted unto themedical wards of UCTH over a 5 year period were analysed. The records of diabetic patients were retrieved. Data on patient characteristics and possible risk factors for diabetes mellitus foot ulcers was extracted. Of the 3,882 patients admitted, 297 (7%) were on account of complications of diabetes mellitus. Foot ulcers accounted for 63 (21.2%) of all diabetic admissions. The elderly constituted the majority of patients admitted with foot ulcers. The average duration of stay of diabetics with foot ulcers was 38.5 days. Diabetics admitted for other conditions had average duration of admission of 15.8 days. Staphylococcus aureus was the commonest organism isolated fromswabs of foot ulcers. Most of the organisms identified fromulcer swab cultures were sensitive to quinolones and resistant to penicillins. These diabetic foot ulcers were significantly associated with peripheral sensory neuropathy, peripheral vascular disease, intermittent claudication, and walking barefoot. An effective diabetes foot programme is required to address these risk factors and reverse the current trend.


Related Articles

  • Activity of Trovafloxacin Against Micro-Organisms Isolated from Diabetic Patients with Lower Extremity Infections. Weiss, K.; Laverdiére, M.; Restieri, C.; Poirier, L. // Drugs;Dec1999 Supplement 2, Vol. 58 Issue 6, p154 

    Examines the in vitro activity of quinolones against microorganisms isolated from patients with diabetic foot infections. Methods; Results; Discussion.

  • Quinolone Resistance Is Associated with Increased Risk of Invasive Illness or Death during Infection with Salmonella Serotype Typhimurium.  // Journal of Infectious Diseases;11/1/2004, Vol. 190 Issue 9, p1652 

    In a registry-based cohort study, we determined the risk of invasive illness or death associated with infection with quinolone-resistant Salmonella serotype Typhimurium. We linked data from the Danish surveillance registry of enteric pathogens with data from the Danish civil registration system...

  • Antimicrobial-Resistant Nontyphoidal Salmonella Is Associated with Excess Bloodstream Infections and Hospitalizations. Varma, Jay K.; Mølbak, Kåre; Barrett, Timothy J.; Beebe, James L.; Jones, Timothy F.; Rabatsky-Ehr, Therese; Smith, Kirk E.; Vugia, Duc J.; Chang, Hwa-Gan H.; Angulo, Frederick J. // Journal of Infectious Diseases;2/15/2005, Vol. 191 Issue 4, p554 

    Background. Nontyphoidal Salmonella is a leading cause of foodborne illness. Few studies have explored the health consequences of antimicrobial-resistant Salmonella. Methods. The National Antimicrobial Resistance Monitoring System (NARMS) performs susceptibility testing on nontyphoidal...

  • Moxifloxacin monotherapy compared to amoxicillin-clavulanate plus roxithromycin for nonsevere community-acquired pneumonia in adults with risk factors. Portier, H.; Brambilla, C.; Garre, M.; Paganin, F.; Poubeau, P.; Zuck, P. // European Journal of Clinical Microbiology & Infectious Diseases;Jun2005, Vol. 24 Issue 6, p367 

    The objective of this study was to assess the efficacy and safety of moxifloxacin versus amoxicillin-clavulanate plus roxithromycin (comparator) in adult community-acquired pneumonia (CAP) patients with risk factors. In this comparative, randomized, multicenter, open-label study, patients...

  • BACTERIOLOGICAL PROFILE AND ANTIBIOGRAM OF NEONATAL SEPTICEMIA. Bhatt, Sima K.; Patel, Disha A.; Gupta, Praveg; Patel, Kiran; Joshi, Gurudutt // National Journal of Community Medicine;Apr-Jun2012, Vol. 3 Issue 2, p238 

    Background: Early diagnosis and proper management of neonatal septicemia can bring down the morbidity and mortality substantially.4 Hence the aim of this study was to study the bacteriological profile of neonatal septicemia cases and their antibiogram for planning strategy for the management of...

  • Clinical and bacteriological efficacies of sitafloxacin against community-acquired pneumonia caused by Streptococcus pneumoniae: nested cohort within a multicenter clinical trial. Fujita, Jiro; Niki, Yoshihito; Kadota, Jun-ichi; Yanagihara, Katsunori; Kaku, Mitsuo; Watanabe, Akira; Aoki, Nobuki; Hori, Seiji; Tanigawara, Yusuke; Cash, Haley; Kohno, Shigeru // Journal of Infection & Chemotherapy (Springer Science & Business;Jun2013, Vol. 19 Issue 3, p472 

    We evaluated the clinical and bacteriological efficacy of oral sitafloxacin (STFX) in clinically diagnosed community-acquired pneumonia (CAP) caused by Streptococcus pneumoniae. Additionally, we cultured these patient samples to test the minimal inhibitory concentrations (MICs) of levofloxacin...

  • The Clinical and Bacteriological Factors for Optimal Levofloxacin-Containing Triple Therapy in Second-Line Helicobacter pylori Eradication. Tai, Wei-Chen; Lee, Chen-Hsiang; Chiou, Shue-Shian; Kuo, Chung-Mou; Kuo, Chung-Huang; Liang, Chih-Ming; Lu, Lung-Sheng; Chiu, Chien-Hua; Wu, Keng-Liang; Chiu, Yi-Chun; Hu, Tsung-Hui; Chuah, Seng-Kee // PLoS ONE;Aug2014, Vol. 9 Issue 8, p1 

    Quinolone has the disadvantage of easily acquired drug resistance. It is important to prescribe it wisely for a high eradication rate. The current study aimed to determine the clinical and bacteriological factors for optimal levofloxacin-containing triple therapies in second-line H. pylori...

  • New study finds dysglycemia risk. Elliott, William T. // Clinical Cardiology Alert;Oct2013 Pharmacology Watch, p1 

    The article focuses on the results of the study from Taiwan regarding the risk of dysglycemia. It mentions that the study was participated by more than 78,000 diabetic patients receiving fluoroquinolones, who were evaluated for dysglycemia including hypoglycemia and hyperglycemia. According to...

  • Antibiotics raise risk of developing diabetes.  // GP: General Practitioner;4/6/2015, p1 

    The article focuses on a study by the researchers of the University of Pennsylvania which shows that the repeated use of some antibiotics is linked to increased risk of type 2 diabetes. The findings include eight percent higher risk of type 2 diabetes in patients who took two to five courses of...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics