Production and Mechanical Properties of Commercial Synthetic Hydroxyapatite (CSHA) Composites

Demirkol, Nermin; Oktar, Faik Nuzhet; Kayali, Eyup Sabri
April 2014
Key Engineering Materials;2014, Vol. 587, p147
Academic Journal
Hydroxyapatite (HA), one of the calcium phosphate compounds, is the most widely used bioceramic. HA materials have a common usage in bone repairing due to its ability to accelerate the bone growth around the implant. HA is a biocompatible material and used in production of various kinds of prosthesis, repairing the cracked or broken bones and coating of metallic biomaterials. This study covers production and characterization of composite materials made of commercial synthetic hydroxyapatite (CSHA) with commercial inert glass, magnesium oxide and niobium (V) oxide additions (5 and 10 wt%), seperately. These additives used as reinforcement materials to improve the mechanical properties of CSHA based composites. The composites were subjected to sintering at different temperatures between 1000°C and 1300°C, then microstructures and mechanical properties of CSHA composites were investigated. The physical and mechanical properties were determined by measuring density, compression strength and Vickers microhardness (HV). Structural characterization was carried out with X-ray diffraction (XRD) and scanning electron microscopy (SEM) studies. In all composites, density values and mechanical properties increased with increasing sintering temperature. CSHA composite with 5 wt% CIG addition showed highest physical and mechanical properties among all CSHA composites produced in this study.


Related Articles

  • Relationship between Osteoinductive Characteristics of Biocomposite Material and Physicochemical Characteristics of Coating. Fedorova, M. Z.; Nadezhdin, S. V.; Kolobov, Yu. R.; Ivanov, M. B.; Pavlov, N. A.; Zubareva, E. V. // Bulletin of Experimental Biology & Medicine;Nov2009, Vol. 148 Issue 5, p822 

    The osteoinductive characteristics of hydroxylapatite-based coating with different physicochemical characteristics were studied. The formation of the bone tissue on the studied types of the implant coating differed by the pattern and rate of formation of structural elements of the bone....

  • Electrically Active Bioceramics: A Review of Interfacial Responses. BAXTER, F. R.; BOWEN, C. R.; TURNER, I. G.; DENT, A. C. E. // Annals of Biomedical Engineering;Jun2010, Vol. 38 Issue 6, p2079 

    Electrical potentials in mechanically loaded bone have been implicated as signals in the bone remodeling cycle. Recently, interest has grown in exploiting this phenomenon to develop electrically active ceramics for implantation in hard tissue which may induce improved biological responses. Both...

  • Calcium phosphate ceramics as bone graft substitutes in filling bone tumor defects. Saikia, K. C.; Bhattacharya, T. D.; Bhuyan, S. K.; Talukdar, D. J.; Saikia, S. P.; Jitesh, P. // Indian Journal of Orthopaedics;Apr-Jun2008, Vol. 42 Issue 2, p169 

    Background: Synthetic bio-inert materials are currently used as an alternative to autogenous bone graft. Calcium hydroxyapatite (HA) and Beta tri-calcium phosphate (β-TCP), which belong to the calcium phosphate ceramics group, are biocompatible and osteo-conductive. The purpose of this study...

  • Response of stem cells from different origins to biphasic calcium phosphate bioceramics. Lobo, Sonja; Glickman, Robert; Silva, Wagner; Arinzeh, Treena; Kerkis, Irina // Cell & Tissue Research;Aug2015, Vol. 361 Issue 2, p477 

    Biphasic calcium phosphate (BCP) bioceramics have been successfully applied in a broad variety of presentation forms and with different ratios of hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP). BCPs have been loaded with stem cells from different origins for bone tissue engineering...

  • Histological characterization of the early stages of bone morphogenetic protein-induced osteogenesis. VEHOF; STANFORD // International Journal of Oral & Maxillofacial Implants;Nov/Dec2002, Vol. 17 Issue 6, p890 

    The article discusses research being done on bone morphogenetic protein-induced osteogenesis. It references a study by J. W. M. Vehof et al, published in the 2002 issue of the "Journal of Biomedical Materials Research." The study compared the osteoinductive properties of porous titanium fiber...

  • Assessment of bone ingrowth potential of biomimetic hydroxyapatite and brushite coated porous E-beam structures. Biemond, J.; Eufrásio, Tatiane; Hannink, Gerjon; Verdonschot, Nico; Buma, Pieter // Journal of Materials Science: Materials in Medicine;Apr2011, Vol. 22 Issue 4, p917 

    The bone ingrowth potential of biomimetic hydroxyapatite and brushite coatings applied on porous E-beam structure was examined in goats and compared to a similar uncoated porous structure and a conventional titanium plasma spray coating. Specimens were implanted in the iliac crest of goats for a...

  • Cementless second-generation hydroxyapatite CaP-coated tibial component: an 8.7-year follow-up. Wedemeyer, Christian; Kauther, Max; Bülbül, Miralay; Jäger, Marcus; Peppmüller, Ralf; Bredendiek, Thomas // Archives of Orthopaedic & Trauma Surgery;Dec2012, Vol. 132 Issue 12, p1759 

    Background: This is the first study that reports on the mid-term results of 81 patients suffering from arthritis of the knee, treated with a cementless second-generation hydroxyapatite calcium phosphate (CaP)-coated tibial component. Materials and methods: Seventy-six knees with osteoarthritis...

  • Biological control of apatite growth in simulated body fluid and human blood serum. Juhasz, Judith A.; Best, Serena M.; Auffret, Antony D.; Bonfield, William // Journal of Materials Science: Materials in Medicine;Apr2008, Vol. 19 Issue 4, p1823 

    The surface transformation reactions of bioactive ceramics were studied in vitro in standard K9-SBF solution and in human blood serum (HBS)—containing simulated body fluid (SBF). The calcium phosphate ceramics used for this study were stoichiometric hydroxyapatite (HA), β-tricalcium...

  • Scientometric Evaluation of Research on Bioceramics. JONG-HEON KIM; KYUNG-RAN NOH; OH-JIN KWON; SUNG-BAE CHOI; SANG-CHEOL KIL // Asian Journal of Chemistry;2014, Vol. 26 Issue 5, p1309 

    During the past several years, there has been a major advance in the development of biomedical materials including various ceramic materials for skeletal repair and reconstruction. To understand bioceramics research trends, we investigated total 12,157 research papers published from 2003 to...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics