TITLE

Lower vitamin D status is more common among Saudi adults with diabetes mellitus type 1 than in non-diabetics

AUTHOR(S)
Al-Daghri, Nasser M.; Al-Attas, Omar S.; Alokail, Majed S.; Alkharfy, Khalid M.; Yakout, Sobhy M.; Aljohani, Naji J.; Al Fawaz, Hanan; Al-Ajlan, Abdulrahman S. M.; Sheshah, Eman S.; Al-Yousef, Mansour; Alharbi, Mohammad
PUB. DATE
February 2014
SOURCE
BMC Public Health;2014, Vol. 14 Issue 1, p1
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background Vitamin D deficiency is an increasingly recognized comorbidity in patients with type 1 diabetes mellitus (DMT1), suggesting that vitamin D deficiency might play a role in DMT1. We aimed to determine and compare the vitamin D status of Saudi adults with and without DMT1. Methods A total of 60 Saudi adults with DMT1 from the Diabetes Clinics and 60 non-DM, healthy controls were included in the study. The mean age for those with DMT1 was 25.9 ± 16.1 years versus 36.7 ± 3.6 years among the controls. We measured serum 25-hydroxy vitamin D (25OHD), calcium, cholesterol, blood glucose, HDL, and triglycerides and compared the results between the DMT1 group and control subjects. Results Both the DMT1 and healthy groups had vitamin D deficiency. The mean levels of 25OHD were significantly lower in the DMT1 adults than in the controls (28.1 ± 1.4 nmol/L versus 33.4 ± 1.6 nmol/L). In the DMT1 adults, 66.7% were mildly, 31.7% moderately, and 3.3% severely vitamin D deficient as compared with 41.7% (mildly), 31.7% (moderately), and 5% (severely) in the control group. Overall, 100% of the DMT1 adults and 78% of the healthy children were vitamin D deficient. Conclusion The prevalence of vitamin D deficiency among DMT1 adults was relatively high. Therefore, screening for vitamin D deficiency and supplementation for this population should be warranted.
ACCESSION #
94500049

 

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