Knowledge of Antiretroviral Regimen Dosing and Adherence: A Longitudinal Study

Miller, Loren G.; Liu, Honghu; Hays, Ron D.; Golin, Carol E.; Ye, Zhishen; Beck, C. Keith; Kaplan, Andrew H.
February 2003
Clinical Infectious Diseases;2/15/2003, Vol. 36 Issue 4, p514
Academic Journal
In a cohort of 128 human immunodeficiency virus-infected patients, we found that patients' knowledge of antiretroviral dosing was suboptimal at regimen initiation but improved with time. Poor medication knowledge 8 weeks after regimen initiation was associated with lower adherence and with a lower level of literacy in a multivariate model (P =.03). Because knowledge deficits are common after antiretroviral regimen initiation, clinicians should assess patients' understanding of medication dosing soon after regimen initiation or change.


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