TITLE

Reduced Testosterone Levels in Human Immunodeficiency Virus-Infected Women with Weight Loss and Low Weight

AUTHOR(S)
Huang, Jeannie S.; Wilkie, Stephanie J.; Dolan, Sara; Gallafent, James H.; Aliabadi, Negar; Sullivan, Meghan P.; Grinspoon, Steven
PUB. DATE
February 2003
SOURCE
Clinical Infectious Diseases;2/15/2003, Vol. 36 Issue 4, p499
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Risk factors for hypoandrogenemia among low-weight, human immunodeficiency virus (HIV)-infected patients are not known. Testosterone levels of 69 HIV-infected women with low weight and weight loss were compared with levels for 25 healthy, age- and body mass index-matched control subjects. HIV-infected subjects were of low weight, with a mean (± standard deviation) weight loss of -17.6% ± 9.7% from preillness maximum, and 42% of HIV-infected subjects had a body mass index of <20 kg/m[SUP2]. Forty-nine percent of the HIV-infected population versus 8% of the control population exhibited low free testosterone levels (P < .001). Among HIV-infected women, when we controlled for chronic hepatitis status, age, and time of blood sampling, weight loss of >10% of maximum weight was a significant predictor of low free testosterone levels. Free testosterone levels did not differ by drug class or antiretroviral regimen. In conclusion, decreased androgen levels are common among HIV-infected women reporting significant weight loss, independent of exposure to antiretroviral medications.
ACCESSION #
9424832

 

Related Articles

  • Characteristics of HIV-infected men with low serum testosterone levels. Kopicko, J J; Momodu, I; Adedokun, A; Hoffman, M; Clark, R A; Kissinger, P // International Journal of STD & AIDS;Dec1999, Vol. 10 Issue 12, p817 

    Low levels of serum testosterone may have negative implications on morbidity in HIV-infected men. The purpose of this study was to determine demographic and clinical characteristics that predict low serum testosterone among men attending our HIV clinic. A cross-sectional study of 587...

  • Testosterone Treatments: Why, When, and How? Margo, Katherine; Winn, Robert // American Family Physician;5/1/2006, Vol. 73 Issue 9, p1591 

    Testosterone treatment is controversial for men and even more so for women. Although long-term outcome data are not available, prescriptions for testosterone are becoming more common. Testosterone is used primarily to treat symptoms of sexual dysfunction in men and women and hot flashes in...

  • Androgen Levels in Older Men Who Have or Who Are at Risk of Acquiring HIV Infection. Klein, Robert S.; Yungtai Lo; Santoro, Nanette; Dobs, Adrian S. // Clinical Infectious Diseases;12/15/2005, Vol. 41 Issue 12, p1794 

    Objective. To determine the prevalence of, risk factors for, and clinical manifestations of low androgen levels in older men who have or who are at risk of acquiring human immunodeficiency virus (HIV) infection, we performed a cross-sectional analysis of an observational cohort of men aged...

  • Androgen Deficiency and HIV Infection. Grinspoon, Steven // Clinical Infectious Diseases;12/15/2005, Vol. 41 Issue 12, p1804 

    The article presents the author's comments on androgen deficiency and HIV infection. Hypogonadism is known to be prevalent among HIV-infected men with low weight and wasting. Hypogonadism among men is usually the result of inadequate stimulation from the gonadotrophs and is termed...

  • Risks and Benefits of Late Onset Hypogonadism Treatment: An Expert Opinion. Corona, Giovanni; Vignozzi, Linda; Sforza, Alessandra; Maggi, Mario // World Journal of Men's Health;Aug2013, Vol. 31 Issue 2, p103 

    Late-onset hypogonadism (LOH) is a syndromic condition that has a well-recognized association with sexual and reproductive failure. LOH is frequently associated with chronic conditions including cardiovascular diseases (CVD), obesity, osteoporosis, HIV infection, renal failure, and obstructive...

  • HIV/AIDS and STD Update.  // AIDS Patient Care & STDs;May2008, Vol. 22 Issue 5, p441 

    The article offers news briefs related to development in the field of HIV/AIDS and sexually transmitted diseases (STD). According to a new study, testosterone spray slightly improves sexual satisfaction in premenopausal women. According to a new study, a person's risk of developing tongue cancer...

  • Oxandrolone.  // Reactions Weekly;2/16/2008, Issue 1189, p28 

    The article describes the cases of 3 men with HIV infections, wasting syndrome and hypogonadism who developed decreased sex hormone-binding globulin (SHBG) and testosterone levels, as well as erectile dysfunction, during treatment with oxandrolone. A 44-year-old man reported erectile...

  • Association between Free Testosterone Levels and Anal Human Papillomavirus Types 16/18 Infections in a Cohort of Men Who Have Sex with Men. Hsu, Hilary K.; Brown, Todd T.; Li, Xiuhong; Young, Stephen; Cranston, Ross D.; D’Souza, Gypsyamber; Jacobson, Lisa P.; Martínez-Maza, Otoniel; Seaberg, Eric C.; Margolick, Joseph B.; Jenkins, Frank J.; Moran, Matthew G.; Chua, Kristofer; Bolan, Robert K.; Detels, Roger; Wiley, Dorothy J. // PLoS ONE;Mar2015, Vol. 10 Issue 3, p1 

    Background: Human papillomavirus (HPV) types 16 and 18 cause invasive cervical cancer and most invasive anal cancers (IACs). Overall, IAC rates are highest among men who have sex with men (MSM), especially MSM with HIV infection. Testosterone is prescribed for men showing hypogonadism and...

  • From the Publisher. Collin, Jonathan // Townsend Letter;Apr2013, Issue 357, p6 

    The article discusses various news in medicine. It states that naturopathic care or alternative medicines for human immunodeficiency virus and acquired immune deficiency syndrome should be provided as an addition only to highly active antiretroviral therapy. The highlights of the Las Vegas A4M...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics