Value of Self-Reportable Screening Criteria to Identify Asymptomatic Individuals in the General Population for Urogential Chlamydia trachomatis Infection Screening

Anderson, Berit; Van Valkengoed, Irene; Olesen, Frede; Møller, Jens K.; Østergaard, Lars
April 2003
Clinical Infectious Diseases;4/1/2003, Vol. 36 Issue 7, p837
Academic Journal
Submission of samples from the home allows screening for Chlamydia trachomatis without preceding professional assessment of clinical risk factors. Therefore, a validation of self-reportable information for use as selective screening criteria is needed. We asked a total of 1175 women and 1033 men who participated in an in-home sampling screening study to provide information on behavior and sociodemographic characteristics. In a multivariate model, selective screening criteria were developed on the basis of information from a random part of the tested population (development group), and the validity was assessed for the remaining part of the tested population (validation group). To find all infections, 95% of the subjects had to be screened, and screening 63% of them would have detected 86% of infections. Low predictive values were found when selective screening criteria from other studies were assessed. Selective screening by means of in-home sampling strategies among men and women aged 21-23 years cannot be recommended in the area studied.


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