Endothelin to the rescue?

Haber, Edgar; Lee, Mu-En
July 1994
Nature;7/28/1994, Vol. 370 Issue 6487, p252
Academic Journal
Discusses the potential of the peptide hormone endothelin to protect heart muscle undergoing ischaemia against the shortening of the action potential by catecholamines. Contraction of rings cut from arteries caused by the supernatant from cultured endothelial cells; Basis of the peptides' action; Intracellular signalling by the endothelin receptors; Extrapolating selective studies in animal myocytes to humans.


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