Delayed and immediate hypersensitivity reactions associated with the use of amalgam

McGivern,, B.; Pemberton,, M.; Theaker,, E.; Buchanan,, J.; Thornhill, M.
January 2000
British Dental Journal;1/22/2000, Vol. 188 Issue 2, p73
Academic Journal
Hypersensitivity to the constituents of dental amalgam is uncommon. When it occurs it typically manifests itself as a lichenoid reaction involving a delayed, type IV, cell-mediated hypersensitivity response. Rarely, a more acute and generalised response can occur involving both the oral mucosa and skin. We describe two cases that illustrate the presentation and management of these two types of reaction.


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