TITLE

Age-related histological and zinc content changes in adult nonhyperplastic prostate glands

AUTHOR(S)
Zaichick, Vladimir; Zaichick, Sofia
PUB. DATE
February 2014
SOURCE
Age;Feb2014, Vol. 36 Issue 1, p167
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
To clarify age-related histological and Zn content changes in nonhyperplastic adult prostate glands, a quantitative morphometric and energy-dispersive X-ray fluorescence analyses were performed. The prostates were obtained from autopsies of 63 subjects aged 21-70 years who died mainly from trauma. It was found that histologically normal prostate tissue undergoes substantial changes throughout aging. These changes are reflected in an increase of the percent volume of the glandular lumen for the third to fifth decades, reaching a maximum for the decade 41-50 years. Over the same period, the percent volume of the stroma remains steady, but the percent volume of epithelium decreases, approximately, linearly with age. The percent volume of glandular lumen (reflects the volume of prostatic fluid) in the prostate gland of men aged 41 to 50 years is 1.5-fold higher than that in men aged 21 to 30 years, but the epithelium/lumen (prostatic fluid) ratio is approximately twofold lower. This suggests that accumulation of the prostatic fluid develops from 30 to 50 years of age. This accumulation of the prostatic fluid results in an increase of the Zn mass fraction in the prostate. In turn, when the intraprostatic Zn level exceeds a certain level by the end of the fifth decade, it begins to work as a trigger for different factors, all of which increase the proliferation of stromal cells. Deductions from these results allow possible partial explanations of both relevant prostatic aging mechanisms and the effects of dietary interventions using supplementary Zn.
ACCESSION #
93447560

 

Related Articles

  • TIN AND TINNED DRESS ACCESSORIES FROM MEDIEVAL WROCŁAW (SW POLAND). X-RAY FLUORESCENCE INVESTIGATIONS. Miazga, Beata // Journal of Estonian Archaelogy / Eesti Arheoloogia Ajakiri;2014, Vol. 18 Issue 1, p57 

    This paper presents a non-destructive analytical study of selected archaeological artefacts from the Old Town in Wrocław, SW Poland, by energy-dispersive X-ray fluorescence spectrometry. The analysed specimens included dress accessories that decorated both women.s and men.s clothes in the...

  • Advantages of Using ED-XRF Spectrometers for the Field Analysis of Soil and Sewage Sludge are Detailed in New Application Brief.  // Asian Environmental Technology;Oct/Nov2015, Vol. 19 Issue 4, p9 

    The article offers information on an application brief which reveals the advantages of using energy dispersive X-ray fluorescence (ED-XRF) spectrometers for the field analysis of soil and sewage sludge.

  • ARCHAEOMETALLURGICAL INVESTIGATION OF HISTORICAL COINS. FIERASCU, Radu Claudiu; FIERASCU, Irina // Metalurgia International;2013, Vol. 18 Issue 7, p277 

    The discover of metals and metalworking has made an important mark on the development of human society role reflected in the names of the archaeologieal periods (Copper Age, Bronze Age, Iron Age). From the metal artefacts, coins are probably the most encountered artefacts, offering valuable...

  • ARCHAEOMETALLURGICAL INVESTIGATION OF HISTORICAL COINS. FIERASCU, Radu Claudiu; FIERASCU, Irina // Metalurgia International;2013, Vol. 18 Issue 7, preceding p5 

    The discovery of metals and metalworking has made an important mark on the development of human society role reflected in the names of the archaeological periods (Copper Age, Bronze Age, Iron Age). From the metal artefacts, coins are probably the most encountered artefacts, offering valuable...

  • Physical and Mechanical Properties of Ceramic-Based Recycled Paper-Cullet-Clay. Sahar, Md Rahim Bin; Samah, Khamisah Binti Abu // Journal of Materials Science & Engineering;2011, Vol. 5 Issue 4, p447 

    A series of ceramic based on (x) recycle paper - (80-x) cullet-20 Kaolin clay (where10 ⩽ x ⩽ 45wt%) has successfully been made by slip casting technique followed by sintering at 1000 °C. The ceramic density has been determined using Archimedes method while their hardness has been...

  • Micromachining with ECDM: Research Potentials and Experimental Investigations. Jawalkar, C.S.; Sharma, Apurbba Kumar; Kumar, Pradeep // World Academy of Science, Engineering & Technology;2012, Issue 61, p90 

    Electro Chemical Discharge Machining (ECDM) is an emerging hybrid machining process used in precision machining of hard and brittle non-conducting materials. The present paper gives a critical review on materials machined by ECDM under the prevailing machining conditions; capability indicators...

  • Morphological study of silver sulfide layers on the polypropylene surface. Krylova, Valentina; Alaburdaitė, Rasa; Guobienė, Asta // Chemija;2013, Vol. 24 Issue 1, p30 

    Layers of silver sulfide, Ag2S, on the surface of polypropylene (PP) film were formed by the chemical bath deposition method (CBD). An initial treatment of PP with modifiers is required in order to provide the adherence to the polymer surface. Film samples were characterized by X-ray...

  • Structure of the chondrules and the chemical composition of olivine in meteorite Jesenice. AMBROŽIč, Bojan; ŠTURM, Sašo; JERŠEK, Miha; MIRTIč, Breda // Geologija (0016-7789);2013, Vol. 56 Issue 1, p19 

    This paper presents a mineralogical analysis of various chondrule types and chemical analysis of olivine in different parts of meteorite Jesenice. Quantitative energy-dispersive X-ray spectroscopy with a scanning electron microscope was used in the analyses. The results showed that the chemical...

  • Analytical study of raw Swarna Makshika (Chalcopyrite) and its Bhasma through TEM and EDAX. Mohapatra, Sudhaldev; Bhushan Jha, Chandra // AYU: An International Quarterly Journal of Research in Ayurveda;Apr-Jun2013, Vol. 34 Issue 2, p204 

    Ayurveda, the Indian System of Medicine deals with a number of metals and minerals. Swarna Makshika (SM), a chalcopyrite one such minerals has iron (Fe), copper (Cu), and sulphur (S) as major ingredients along with other trace elements of therapeutic importance. Studies related with...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics