TITLE

SÜNNET ÖNCESİ PRİLOKAİN UYGULANAN BİR YENİDOĞANDA GELİŞEN METHEMOGLOBİNEMİ

AUTHOR(S)
Yanaral, Fatih; Aslan, Ahmet Rüknettin; Çubuk, Alkan; Kökbıyık, Mehmet Taha; Şengör, Feridun
PUB. DATE
September 2013
SOURCE
Nobel Medicus Journal;Sep-Dec2013, Vol. 9 Issue 3, p142
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Circumcision is reported to be the most common surgical procedure performed on newborns. Local anesthesia infiltration by injection is considered to be the most effective method of analgesia for circumcision. Methemoglobinemia is a rare but potentially lethal complication of local anesthetics. We report the case of a newborn who presented with cyanosis due to methemoglobinemia (methemoglobin. 38.5%) following local anesthesia with prilocaine. Cyanosis resolved after administration of 10% dextrose solution, supplemental oxygen (5 lt/min) via hood and intravenous methylene blue (1 mg/kg). Methemoglobinemia must be considered in the differential diagnosis of the cyanotic patient. Prilocaine should not be used in children younger than 6 months, in pregnant women, or in patients taking other oxidizing drugs and the dose of prilocaine should be adjusted according to weight to prevent methemoglobinemia. Methylene blue with supportive therapy is the first-line treatment.
ACCESSION #
93443870

 

Related Articles

  • Benzocaine-induced Methemoglobinemia. Hegedus, Frederick; Herb, Kathleen // Anesthesia Progress;Winter2005, Vol. 52 Issue 4, p136 

    A case is reported in which a patient developed methemoglobinemia-induced cyanosis while under general anesthesia during surgery for multiple fascial space infections. The cause of methemoglobinemia was 20% benzocaine spray used for local anesthesia before intubation. Acutely developing...

  • Benzocaine-Induced Methemoglobinemia A Potentially Fatal Complication of Trasesophageal Echocardiography. Sachdeva, Rajesh; Pugeda, Jaime G.; Casale, Linda R.; Meizlish, Jay L.; Zarich, Stuart W. // Texas Heart Institute Journal;2003, Vol. 30 Issue 4, p308 

    We describe the cases of 2 patients who developed benzocaine-induced methemoglobinemia after the administration of benzocaine as premedication for transesophageal echocardiography. The use of intravenous methylene blue resolved the cyanosis in both patients. Physicians who perform procedures...

  • Methemoglobinemia presenting in a circumcised baby following application of prilocaine: a case report. Ozdogan, Hatice; Osma, Selcan; Aydin, Gozde B.; Dinc, Avni; Ozgun, Gulten // Journal of Medical Case Reports;2010, Vol. 4 Issue 1, p1 

    Introduction: Local anesthesia with prilocaine has become a routine part of ambulatory circumcision procedures. Methemoglobinemia is a rare but potentially lethal complication of local anesthetics. Case presentation: We report the case of a 40-day-old Turkish boy who presented with cyanosis...

  • Prilocaine/felypressin overdose.  // Reactions Weekly;2/19/2011, Issue 1339, p34 

    The article describes the case of a 26-year-old girl who developed methaemoglobinaemia after she was given the dental anesthesia prilocaine/felypressin prior to the extraction of neonatal teeth.

  • Effective penile block for circumcision in adults. Malkoc, Ercan; Ates, Ferhat; Uguz, Sami; Dursun, Furkan; Can, Fuat; Baykal, Kadir // Wiener Klinische Wochenschrift;Jul2012, Vol. 124 Issue 13/14, p434 

    Background: The dorsal nerve block of the penis during circumcision has not been standardized and the effectiveness of the block can be changeable. The aim of this study was to determine which technique is more suitable for blocking sensory innervations of penis. Methods: This prospective study...

  • A newborn with cyanosis. Agbeko, R. S.; Semmekrot, B. A.; Bongaerts, G. P. A.; Neeleman, C.; Severijnen, R. S. V. M. // European Journal of Pediatrics;1998, Vol. 157 Issue 12, p1026 

    Presents a case report of an infant with cyanosis. Treatment given; Signs, symptoms and laboratory parameters of the patient; Analysis of most cases of cyanosis in newborn infants; Conclusions.

  • Glomerulonephritis in a neonate with atypical congenital lupus and toxoplasmosis. Lam, Chun; Imundo, Lisa; Hirsch, Daniel; Yu, Zhimin; D’Agati, V. // Pediatric Nephrology;1999, Vol. 13 Issue 9, p850 

    The development of glomerulonephritis as a complication of neonatal lupus or congenital toxoplasmosis is extremely rare. We report a case of membranous glomerulonephritis occurring in a neonate with toxoplasmosis and atypical congenital lupus, including high-titer antinuclear antibodies and...

  • Prilocaine.  // Reactions Weekly;8/14/2010, Issue 1314, p35 

    The article describes two cases of methaemoglobinaemia in infants after taking prilocaine for local anaesthesia.

  • Hypovolemic Shock after Circumcision. Sarsu, Sevgi Buyukbese; Belen, Burcu // APSP Journal of Case Reports;2014, Vol. 5 Issue 1, p1 

    A letter to the editor is presented which discusses a case study of a 2.5-month-old neonate with hypovolemic shock who was brought with bleeding 12 hours after being circumcised at home by a traditional circumciser.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics