Comparative testing of antimicrobial activity of aqueous extracts of Aloe vera and Lycium barbarium

FIŢ, Nicodim Iosif; CHIRILĂ, Flore; NADĂŞ, George; PALL, Emoke; MUREŞAN, RADU
January 2013
Bulletin of the University of Agricultural Sciences & Veterinary;2013, Vol. 70 Issue 1, p72
Academic Journal
Plants have a very important role in natural medicine because of their composition rich in vitamins, minerals, antimicrobial and immunomodulatory compounds. Since antibioresistance to some antibiotics used in current therapy in human medicine and veterinary medicine is nowadays a major problem, researches have searched for alternative methods of replacement or combination of antibiotics with different plant extracts with antimicrobial and/or immunomodulatory effect. This experiment was designed to evaluate the comparative antimicrobial effect of aqueous extracts of aloe (Aloe vera) and goji berries (Lycium barbarum) on some species of bacteria and fungi. We used for this experiment five kinds of aqueous extracts of aloe vera (two extracted from the for six months old plant, two from a 4 years old plants and a standard commercially available aqueous extract). Five types of aqueous extracts of goji fruit (1/1 goji soak, total aqueous extract, fruit centrifuged supernatant, fruits supernatant filtered through 0.2μm Millipore and watery sediment from plant mortar) were also tested. Four kinds of microorganisms including Gram-positive bacteria (Staphylococcus aureus ATCC 6538P), Gram-negative bacteria (Escherichia coli ATCC 10536, Pseudomonas aeruginosa ATCC 27853) and fungi (Candida albicans ATCC 10231) were used for determining the sensitivity. Testing was done by disc diffusion method with some changes according to the tested compounds. The interpretation of disk diffusion test revealed that Aloe vera extracts had inhibitory effect only on the strains of Staphylococcus aureus ATCC 653 8P, the effect being stronger for total extract (100%) as well as for standardized extract. The growth of Escherichia coli ATCC 10536 strain, was increased instead of being inhibited. On Candida albicans ATCC 10231 strain, only standardized extract had a good inhibitory effect. Regarding the antimicrobial effect of aqueous extracts of goji fruit we found a weak inhibitory effect, however, observing a strong inhibitory effect on E. coli strain. This study demonstrated that aqueous extracts of aloe and goji have antimicrobial effect, which depends on the concentration of the extract and the type of microorganism tested. The results can represent a prospect into the use of these extracts as substitutes for antibiotics or along with antibiotics and may have practical applications in medicine, cosmetics and food industry.


Related Articles

  • Laxative potential of the ethanolic leaf extract of Aloe vera (L.) Burm. f. in Wistar rats with loperamide-induced constipation. Ashafa, A. O. T.; Sunmonu, T. O.; Abass, A. A.; Ogbe, A. A. // Journal of Natural Pharmaceuticals;Jul2011, Vol. 2 Issue 3, p158 

    Background: Constipation is a highly prevalent and often chronic functional gastrointestinal disorder affecting humans irrespective of race and color exposing victims to colorectal cancer. The present study evaluated the efficacy of the ethanolic leaf extract of Aloe vera against...

  • Hepatotherapeutic Effect of Aloe Vera in Alcohol-induced Hepatic Damage. Saka, W. A.; Akhrgbe, R. E.; Ishola, O. S.; Ashamu, E. A.; Olayemi, O. T.; Adeleke, G. E. // Pakistan Journal of Biological Sciences;7/15/2011, Vol. 14 Issue 14, p742 

    There is a lack of reliable hepatotherapeutic drugs in modern medicine in the management of alcohol/drug-induced liver damage. Aloe vera extract has been used in folklore medicine for its medicinal values. This study evaluates the hepatotherapeutic activity of aqueous extract of Aloe vera gel in...

  • Screening of Antimicrobial Activity of Alcoholic & Aqueous Extract of Some Indigenous Plants. Johnson, D. Benito; Shringi, B. N.; Patidar, Dinesh Kumar; Suresh Chalichem, Nehru Sai; Javvadi, Ashok Kumar // Indo Global Journal of Pharmaceutical Sciences;2011, Vol. 1 Issue 2, p186 

    Plants known to possess several antimicrobial compounds are used in all traditional medicine. Our study was to screen the leaf extracts of Aloe vera, Datura stromonium, pongamia pinnata, Lantona camara, Calotropis procera. These plants were collected and aqueous and alcoholic extracts were...

  • Whole plant extracts versus single compounds for the treatment of malaria: synergy and positive interactions. Rasoanaivo, Philippe; Wright, Colin W.; Willcox, Merlin L.; Gilbert, Ben // Malaria Journal;2011 Supplement 1, Vol. 10 Issue Suppl 1, p1 

    Background: In traditional medicine whole plants or mixtures of plants are used rather than isolated compounds. There is evidence that crude plant extracts often have greater in vitro or/and in vivo antiplasmodial activity than isolated constituents at an equivalent dose. The aim of this paper...

  • Antibacterial Effect of Essential Vegetal Extracts on Staphylococcus aureus Compared to Antibiotics. FIT, Iosif Nicodim; RAPUNTEAN, Gheorghe; RAPUNTEAN, Sorin; CHIRILA, Flore; NADAS, George Cosmin // Notulae Botanicae Horti Agrobotanici Cluj-Napoca;2009, Vol. 37 Issue 2, p117 

    This study is aiming to evaluate the antimicrobial activity of ten essential vegetal extracts on strains of Staphylococcus aureus isolated from animal lesions. The comparative effect of some antibiotics on these strains isolated from animals was also tested and estimated. The extracts were...

  • Critical Study of Aloe ferox in view of Ayurveda. Ayurvedavaridhi, Sharduli Rajiv Terwadkar; Ayurvedavaridhi, P. H. Kulkarn // Internet Journal of Alternative Medicine;2008, Vol. 5 Issue 2, p1 

    South Africa & India have rich heritage of ancient wisdom and their Traditional Medicinal Systems are part of it. Aloe ferox is compared with Aloe vera on the basis of Ayurvedic principles & other theories. This is theoretical research & can lead to many interesting researches. On the basis of...

  • loving! Aloe vera.  // Cleo;Feb2003, Issue 364, p158 

    Offers information on underwears and on a deodorant that feature aloe vera extracts. Manufacturer; Price.

  • Effect of Fig (Ficus carica) Leaf Extract on the Secretion and Content of Cholesterol in Hepg2 Cell. Fatemi, Ahmad; Rasouli, Ali; Asadi, Farzad // American Journal of Animal & Veterinary Sciences;2007, Vol. 2 Issue 4, p104 

    Traditional medicines remain a source of potential for discovering of new compounds with valuable pharmacological activities. Leaves of Ficus carica were dried, powdered and extracted using methanol (ME).An aliquot of ME was dried and re-extracted by water:chloroform and the other aliquot by...

  • Insecticidal, antimicrobial, phyto- and cytotoxicity of Chassalia kolly plant extract. Onocha, Patricia Akpomedaye; Ali, Shaiq Muhammad // Archives of Applied Science Research;2010, Vol. 2 Issue 4, p151 

    Chassalia kolly (Schumach.) Hepper (Rubiaceae) is used in ethno-medical practices particularly in Nigeria and the West African sub-region for the treatment of typhoid and fevers that are endemic in Nigeria as well as in the tropics and as an insect repellant. The methanolic extract of the dried...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics