TITLE

Avian-Origin Influenza A(H7N9) Infection in Influenza A(H7N9)–Affected Areas of China: A Serological Study

AUTHOR(S)
Yang, Shigui; Chen, Yu; Cui, Dawei; Yao, Hangping; Lou, Jianzhou; Huo, Zhaoxia; Xie, Guoliang; Yu, Fei; Zheng, Shufa; Yang, Yida; Zhu, Yixin; Lu, Xiaoqing; Liu, Xiaoli; Lau, Siu-Ying; Chan, Jasper Fuk-Woo; To, Kelvin Kai-Wang; Yuen, Kwok-Yung; Chen, Honglin; Li, Lanjuan
PUB. DATE
January 2014
SOURCE
Journal of Infectious Diseases;Jan2014, Vol. 209 Issue 2, p265
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Serological surveillance conducted in areas of an outbreak of influenza A(H7N9) infection in China found no seropositivity for antibodies specific for avian-origin influenza A(H7N9) among 1129 individuals of the general population, whereas >6% of 396 poultry workers were positive (on the basis of a hemagglutination inhibition titer of ≥ 80) for this subtype, confirming that infected poultry is the principal source of human infections and that subclinical infections are possible. Fourteen days after symptom onset, elevated levels of antibodies to A(H7N9) were found in 65.8% of patients (25/38) who survived but in only 28.6% of those (2/7) who died, suggesting that the presence of antibodies may improve clinical outcome in infected patients.
ACCESSION #
93399105

 

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