TITLE

BACs to the future: new genetic models for cardiovascular discovery

AUTHOR(S)
Kotlikoff, Michael I.
PUB. DATE
January 2014
SOURCE
Cardiovascular Research;Jan2014, Vol. 101 Issue 1, p7
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
93398943

 

Related Articles

  • Natriuretic Peptide Signaling via Guanylyl Cyclase (GC)-A: An Endogenous Protective Mechanism of the Heart. Kishimoto, Ichiro; Tokudome, Takeshi; Horio, Takeshi; Garbers, David L.; Nakao, Kazuwa; Kangawa, Kenji // Current Cardiology Reviews;2009, Vol. 5 Issue 1, p45 

    Atrial and brain natriuretic peptides (ANP and BNP, respectively) are cardiac hormones, secretions of which are markedly upregulated during cardiac failure, making their plasma levels clinically useful diagnostic markers. ANP and BNP exert potent diuretic, natriuretic and vasorelaxant effects,...

  • Natriuretic peptides modulate ATP-sensitive K channels in rat ventricular cardiomyocytes. Burley, Dwaine; Cox, Charles; Zhang, Jin; Wann, Kenneth; Baxter, Gary // Basic Research in Cardiology;Mar2014, Vol. 109 Issue 2, p1 

    B-type natriuretic peptide (BNP) and C-type natriuretic peptide (CNP), and (Cys-18)-atrial natriuretic factor (4-23) amide (C-ANF), are cytoprotective under conditions of ischemia-reperfusion, limiting infarct size. ATP-sensitive K channel (K) opening is also cardioprotective, and although the K...

  • Atrial natriuretic factor-receptor guanylate cyclase signal transduction mechanism. Teresa Duda // Molecular & Cellular Biochemistry;Jan2010, Vol. 334 Issue 1/2, p37 

    Abstract  Atrial natriuretic factor (ANF) receptor guanylate cyclase (ANF-RGC), like the other members of the membrane guanylate cyclase family, is a single transmembrane-spanning protein. The transmembrane domain separates the protein into two regions, extracellular and...

  • Atrial natriuretic factor receptor guanylate cyclase signaling: new ATP-regulated transduction motif. Teresa Duda; Ireneusz Wojtas; Prem Yadav; Rameshwar Sharma // Molecular & Cellular Biochemistry;Apr2009, Vol. 324 Issue 1/2, p39 

    Abstract  ANF-RGC membrane guanylate cyclase is the receptor for the hypotensive peptide hormones, atrial natriuretic factor (ANF) and type B natriuretic peptide (BNP). It is a single transmembrane spanning protein. Binding the hormone to the extracellular domain activates its...

  • Potential Association Between Frequent Nonsynonymous Variant of NPPA and Cardioembolic Stroke. Kim, Jeong-Hyun; Jang, Bo-Hyung; Go, Ho Yeon; Park, Sunju; Shin, Yong-Cheol; Kim, Sung-Hoon; Ko, Seong-Gyu // DNA & Cell Biology;Jun2012, Vol. 31 Issue 6, p993 

    Atrial natriuretic peptide (ANP, also known as NPPA) and brain natriuretic peptide (BNP, also known as NPPB) have been determined as genetic factors for several diseases, including stroke and myocardial infarction, in human and rat models. To investigate the potential association between...

  • EL CORAZÓN ENDOCRINO Y EL PROCESO INFLAMATORIO. OGAWA, TSUNEO; DE BOLD, ADOLFO J. // Medicina (Buenos Aires);2013, Vol. 73 Issue 6, p562 

    The endocrine heart produces the polypeptide hormones Atrial Natriuretic Factor (ANF or ANP) and Brain Natriuretic Peptide (BNP). Through the peripheral actions of these hormones the heart contributes to the regulation of the cardiac preload and afterload. More recently, new functions for these...

  • B-type natriuretic peptide and echocardiographic indices of left ventricular filling in critically ill patients with severe sepsis: a cohort study. Douglas, K.; Hillis, G. S.; Croal, B. L.; Gibson, P.; Cuthbertson, B. H. // BJA: The British Journal of Anaesthesia;Nov2014, Vol. 113 Issue 5, p884 

    No abstract available.

  • Assessing prognosis of pulmonary embolism using tissue-Doppler echocardiography and brain natriuretic peptide. Tude Rodrigues, Ana Clara; Cordovil, Adriana; Gianini Mônaco, Cláudia; Bonfim Guimarães, Laise Antônia; Alves de Oliveira, Wércules Antônio; Henrique Fischer, Claudio; Bezerra de Lira-Filho, Edgar; Campos Vieira, Marcelo Luiz; Saady Morhy, Samira // Einstein (16794508);Jul-Sep2013, Vol. 11 Issue 3, p338 

    Objective: To assess prognosis of pulmonary thromboembolism using tissue Doppler echocardiography and brain natriuretic peptide. Methods: Patients aged over 18 years were evaluated within 24 hours of confirmed diagnosis (chest tomography/pulmonary scintigraphy) of pulmonary embolism using...

  • Pressure Overload-Induced Cardiac Hypertrophy Response Requires Janus Kinase 2-Histone Deacetylase 2 Signaling. Huang Ying; Mao-Chun Xu; Jing-Hua Tan; Jing-Hua Shen; Hao Wang; Dai-Fu Zhang // International Journal of Molecular Sciences;2014, Vol. 15 Issue 11, p20240 

    Pressure overload induces cardiac hypertrophy through activation of Janus kinase 2 (Jak2), however, the underlying mechanisms remain largely unknown. In the current study, we tested whether histone deacetylase 2 (HDAC2) was involved in the process. We found that angiotensin II (Ang-II)-induced...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics