TITLE

MicroRNA-221 promotes colorectal cancer cell invasion and metastasis by targeting RECK

AUTHOR(S)
Qin, Jun; Luo, Meng
PUB. DATE
January 2014
SOURCE
FEBS Letters;Jan2014, Vol. 588 Issue 1, p99
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Highlights: [•] miR-221 is upregulated in metastatic CRC cell lines and tissues. [•] miR-221 promotes cell migration and invasion in CRC cells. [•] miR-221 promotes liver metastases in vivo. [•] RECK is a direct target of miR-221 and reduces miR-221-induced CRC cell invasiveness. [•] miR-221 and RECK protein expression are inversely correlated in CRC tissues.
ACCESSION #
93334797

 

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