Homocysteine-lowering therapy improved outcomes after percutaneous coronary intervention
- Homocysteine-induced vascular dysregulation is mediated by the NMDA receptor. Qureshi, Irfan; Hongjiang Chen; Brown, Aliza T.; Fitzgerald, Ryan; Xingjian Zhang; Breckenridge, Julie; Kazi, Rafi; Crocker, Amy J.; Stühlinger, Markus C.; Lin, Kenneth; Cooke, John P.; Eidt, John F.; Moursi, Mohammed M. // Vascular Medicine;2005, Vol. 10 Issue 3, p215
Elevated plasma homocysteine accelerates myointimal hyperplasia and luminal narrowing after carotid endarterectomy. N-methyl D aspartate receptors (NMDAr) in rat cerebrovascular cells are involved in homocysteine uptake and receptor-mediated stimulation. In the vasculature, NMDAr subunits (NR1,...
- Vitamin therapy to reduce homocysteine levels halts the progression of carotid atherosclerosis. // Geriatrics;Apr2000, Vol. 55 Issue 4, p85
Investigates the effectiveness of vitamin therapy such as folic acid and vitamins B6 and B12 on lowering the homocysteine levels. Reduction of the progression of carotid artherosclerosis of patients with vascular diseases. Studies conducted on the effectiveness of vitamins.
- Nutritional hyperhomocysteinaemia. Mohan, I.V.; Stansby, G // BMJ: British Medical Journal (International Edition);06/12/99, Vol. 318 Issue 7198, p1569
Editorial. Looks at the evidences of the effect of high concentration of serum homocysteine as a risk factor for clinical vascular disease. Information on homocysteine; Clinical findings of nutritional studies on patients with vascular disease.
- Hiper-homocisteinemia como fator de risco cardiovascular. de Moura, Mayara Storel Beserra; Martins, Maria do Carmo de Carvalho e; Filho, Manoel Dias de Souza // ConScientiae Saude;2011, Vol. 10 Issue 1, p181
Introduction: Hyperhomocysteinemia has been identified as a risk factor for peripheral vascular disease. Objective: The main objective was doing a review of literature on homocysteine as a risk factor for cardiovascular disease. Methods: It was performed a descriptive bibliographic research in...
- THROMBOTIC ISCHEMIC STROKE IN A CASE WITH MODERATE HYPERHOMOCYSTEINEMIA. STOICĂNESCU, DORINA; CEVEI, MARIANA; SUCIU, RAMONA // Acta Medica Transilvanica;dec2013, Vol. 18 Issue 4, p193
Increased concentration of homocysteine is a risk factor for stroke, peripheral vascular disease, myocardial infarction, and venous thromboembolism. It seems that hyperhomocysteinemia affects not only the blood coagulation system, but also the vascular wall structure. MTHFR gene encodes a...
- Plasma Homocysteine is Not Related to the Severity of Microangiopathy in Secondary Raynaud Phenomenon. Jacomella, Vincenzo; Wasila, Monika; Husmann, Marc; Gitzelmann, Gabriela; Meier, Thomas; Amann-Vesti, Beatrice // Open Rheumatology Journal;2011, Vol. 5, p64
Introduction: The role of elevated homocysteine in primary and secondary Raynaud phenomenon (RP) and in patients with atherosclerosis has been reported controversially. In secondary RP due to connective tissue disease specific alterations of nailfold capillaries might be present. An association...
- Update on Selected Markers Used in Risk Assessment for Vascular Disease. Carreiro-Lewandowski, Eileen // Clinical Laboratory Science;Winter2004, Vol. 17 Issue 1, p43
Presents information on the markers used in risk assessment for cardiovascular vascular disease (CVD). Characteristics of CVD; Link between endothelial dysfunction and CVD; Significance of elevated homocysteine levels to CVD risk.
- The effect of MTHFR c.677C>T on plasma homocysteine levels depends on health, age and smoking. Semmler, Alexander; Moskau, Susanna; Stoffel-Wagner, Birgit; Weller, Michael; Linnebank, Michael // Clinical & Investigative Medicine;Dec2009, Vol. 32 Issue 6, pE310
Purpose: The role of homocysteine in the pathogenesis of arteriosclerosis and stroke is under debate. It is important to determine the interplay of factors that influence homocysteine plasma levels, such as age, gender, smoking and the genetic background. The T-allele of the common variant...
- Effect of Glycemic Control on Homocysteine Levels in Type 2 Diabetic Patients without Cardiovascular Disease. Heydari-Zarnagh, Hafez; Nejat-Shookohi, Amireh; Nourozi, Abdolreza // Zahedan Journal of Research in Medical Sciences;Jan2014, Vol. 16 Issue 1, p23
Background: An increased serum homocysteine level was accepted as an important risk factor for vascular disease, including coronary atherosclerosis. However, there was no data about the importance of glycemic control on homocysteine levels in type 2 diabetic patients without CVD. The aim of this...