TITLE

I -123 metaiodobenzylguanidine imaging for predicting ventricular arrhythmia in heart failure patients

AUTHOR(S)
Weihua Zhou; Ji Chen
PUB. DATE
November 2013
SOURCE
Journal of Biomedical Research;2013, Vol. 27 Issue 6, p460
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Compared to antiarrhythmic drugs, implantable cardioverter defibrillator (ICD) leads to a more significant improvement in preventing ventricular arrhythmia in heart failure patients. However, an important question has been raised that how to select appropriate patients for ICD therapy. I-123 metaiodobenzylguanidine (MIBG) planar and SPECT imaging have shown great potentials to predict ventricular arrhythmia in heart failure patients by assessing the abnormalities of the sympathetic nervous system. Clinical trials demonstrated that several parameters measured from I-123 MIBG planar and SPECT imaging, such as heart-to-mediastinum ratio, washout rate, defect score, and innervation/perfusion mismatch, predicted ventricular arrhythmias in heart failure patients. This paper introduces the current practice of ICD therapy and reviews the technical background of I-123 MIBG planar and SPECT imaging and their clinical data in predicting ventricular arrhythmia.
ACCESSION #
92734213

 

Related Articles

  • ORAL ABSTRACT SESSION: CLINICAL.  // European Journal of Heart Failure;May2013 Supplement, Vol. 12, pS17 

    No abstract available.

  • I-123 mIBG and Tc-99m myocardial SPECT imaging to predict inducibility of ventricular arrhythmia on electrophysiology testing: A retrospective analysis. Zhou, Yanli; Zhou, Weihua; Folks, Russell; Manatunga, Daya; Jacobson, Arnold; Bax, Jeroen; Garcia, Ernest; Chen, Ji // Journal of Nuclear Cardiology;Oct2014, Vol. 21 Issue 5, p913 

    Objectives: The purpose of this study is to assess mIBG uptake in scar border zone and its relation with ventricular arrhythmia (VA) inducibility on electrophysiology (EP) testing using I-123 mIBG SPECT and resting Tc-99m SPECT myocardial perfusion imaging (MPI). Methods: Forty-seven patients...

  • Nuclear imaging modalities for cardiac amyloidosis. Bokhari, Sabahat; Shahzad, Reehan; Castaño, Adam; Maurer, Mathew // Journal of Nuclear Cardiology;Feb2014, Vol. 21 Issue 1, p175 

    Amyloidosis is a heterogeneous group of diseases characterized by localized or systemic deposition of insoluble extracellular fibrillary proteins in organs and tissues. Several types of amyloid can infiltrate the heart resulting in a restrictive cardiomyopathy, heart failure, and atrial and...

  • In search of the perfect indicators of left ventricular mechanical dyssynchrony. Borges-Neto, Salvador; Samad, Zainab // Journal of Nuclear Cardiology;Dec2015, Vol. 22 Issue 6, p1259 

    No abstract available.

  • Sjögren's Syndrome.  // Current Medical Literature: Rheumatology;2010, Vol. 29 Issue 2, p58 

    The article discusses a research study on which investigated the relationship between cognitive function and technecium-99m-ethyl cysteinate dimer single-photon emission computed tomography (SPECT) in patients with primary Sjögren's syndrome. It reference a study by V. Le Guern et al,...

  • Poster Presentations.  // European Journal of Nuclear Medicine & Molecular Imaging;Sep2009 Supplement 2, Vol. 36, p281 

    The article presents abstracts on diagnostic technology which include the therapeutic use of Ioflupane I123 brain single photon emission computed tomography (SPECT) in Movement Disorder patients, a software tool to trace epileptogenic foci in intractable partial epilepsy, and the automated...

  • Arterial Spin Labeling: Experiência Inicial, Indicações Clínicas e Dificuldades. CARNEIRO, Angelo; PINA, Sofia; MOREIRA, Bruno // Acta Medica Portuguesa;Jul/Aug2012, Vol. 25 Issue Supp 1, p1 

    Arterial spin labelling (ASL) is a MR perfusion technique that uses protons from water molecules of the arterial blood as an endogenous tracer. It is fast, non-invasive and does not require gadolinium administration. Due to the increasing robustness of the results, it is becoming an important...

  • Does cognitive profile distinguish Lewy body disease from Alzheimer's disease in the early stages? Blanc, F. // Journal of Neurology, Neurosurgery & Psychiatry;Dec2013, Vol. 84 Issue 12, p1299 

    The author discusses the strategies used to distinguish between patients of neurodegenerative disorders, Lewy body disease (LBD) and Alzheimer's disease (AD). He reports that single-photon emission computed tomography (SPECT) is used in the differentiation but it is very costly. He suggests that...

  • Predictive value of brain perfusion SPECT for ketamine response in hyperalgesic fibromyalgia. Guedj, Eric; Cammilleri, Serge; Colavolpe, Cecile; Taieb, David; Laforte, Catherine; Niboyet, Jean; Mundler, Olivier // European Journal of Nuclear Medicine & Molecular Imaging;Aug2007, Vol. 34 Issue 8, p1274 

    Ketamine has been used successfully in various proportions of fibromyalgia (FM) patients. However, the response to this specific treatment remains largely unpredictable. We evaluated brain SPECT perfusion before treatment with ketamine, using voxel-based analysis. The objective was to determine...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics