TITLE

Choosing CCR5 or Rev siRNA in HIV-1

AUTHOR(S)
Arteaga, H. Jose; Hinkula, Jorma; van Dijk-Hard, Iris; Dilber, M. Sirac; Wahren, Britta; Christensson, Birger; Mohamed, Abdalla J.; Edvard Smith, C. I.
PUB. DATE
March 2003
SOURCE
Nature Biotechnology;Mar2003, Vol. 21 Issue 3, p230
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Reacts to reports in 'Nature Biotechnology' and in 'Nature' that demonstrate that small inhibitory RNAs (siRNAs) efficiently target and degrade human immunodeficiency virus (HIV)-1 RNA sequences and inhibit viral replication. Reactors' view that treatments limited to the inhibition of viral products by siRNA will not be clinically feasible.
ACCESSION #
9220298

 

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