TITLE

New relationships of human hematopoietic lineages facilitate detection of multipotent hematopoietic stem and progenitor cells

AUTHOR(S)
Görgens, André; Radtke, Stefan; Horn, Peter A.; Giebel, Bernd
PUB. DATE
November 2013
SOURCE
Cell Cycle;11/15/2013, Vol. 12 Issue 22, p3478
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
No abstract available.
ACCESSION #
91986795

 

Related Articles

  • Circulating hematopoietic progenitors with T lineage potential. Schwarz, Benjamin A.; Bhandoola, Avinash // Nature Immunology;Sep2004, Vol. 5 Issue 9, p953 

    The thymus is seeded via the blood, but the identity of hematopoietic progenitors with access to the circulation in adult mice is unknown. We report here that the only progenitors in blood with efficient T lineage potential were lineage negative with high expression of stem cell antigen 1 and...

  • A Novel Serum-Free Monolayer Culture for Orderly Hematopoietic Differentiation of Human Pluripotent Cells via Mesodermal Progenitors. Niwa, Akira; Heike, Toshio; Umeda, Katsutsugu; Oshima, Koichi; Kato, Itaru; Sakai, Hiromi; Suemori, Hirofumi; Nakahata, Tatsutoshi; Saito, Megumu K. // PLoS ONE;2011, Vol. 6 Issue 7, p1 

    Elucidating the in vitro differentiation of human embryonic stem (ES) and induced pluripotent stem (iPS) cells is important for understanding both normal and pathological hematopoietic development in vivo. For this purpose, a robust and simple hematopoietic differentiation system that can...

  • A Novel Serum-Free Monolayer Culture for Orderly Hematopoietic Differentiation of Human Pluripotent Cells via Mesodermal Progenitors. Niwa, Akira; Heike, Toshio; Umeda, Katsutsugu; Oshima, Koichi; Kato, Itaru; Sakai, Hiromi; Suemori, Hirofumi; Nakahata, Tatsutoshi; Saito, Megumu K. // PLoS ONE;2011, Vol. 6 Issue 7, p1 

    Elucidating the in vitro differentiation of human embryonic stem (ES) and induced pluripotent stem (iPS) cells is important for understanding both normal and pathological hematopoietic development in vivo. For this purpose, a robust and simple hematopoietic differentiation system that can...

  • The Role of a Human Hematopoietic Mesenchymal Progenitor in Wound Healing and Fibrotic Diseases and Implications for Therapy. Mattoli, Sabrina; Bellini, Alberto; Schmidt, Matthias // Current Stem Cell Research & Therapy;Dec2009, Vol. 4 Issue 1, p266 

    The human peripheral blood contains a multipotent precursor that shows hematopoietic stem cell features and transiently expresses markers of the myeloid lineage. Under permissive conditions, this precursor gives rise to committed progenitors of various lineages, including a mesenchymal...

  • Hematopoietic developmental pathways: on cellular basis. Iwasaki, H.; Akashi, K. // Oncogene;10/15/2007, Vol. 26 Issue 47, p6687 

    To elucidate the molecular mechanisms underlying normal and malignant hematopoietic development, it is critical to identify developmental intermediates for each lineage downstream of hematopoietic stem cells. Recent advances in prospective isolation of hematopoietic stem and progenitor cells,...

  • Hematopoietic cell differentiation from embryonic and induced pluripotent stem cells. Wai Feng Lim; Tomoko Inoue-Yokoo; Keai Sinn Tan; Lai, Mei I.; Daisuke Sugiyama // Stem Cell Research & Therapy;2013, Vol. 4 Issue 3, p1 

    Pluripotent stem cells, both embryonic stem cells and induced pluripotent stem cells, are undifferentiated cells that can self-renew and potentially differentiate into all hematopoietic lineages, such as hematopoietic stem cells (HSCs), hematopoietic progenitor cells and mature hematopoietic...

  • The transcriptional architecture of early human hematopoiesis identifies multilevel control of lymphoid commitment. Laurenti, Elisa; Doulatov, Sergei; Zandi, Sasan; Plumb, Ian; Chen, Jing; April, Craig; Fan, Jian-Bing; Dick, John E // Nature Immunology;Jul2013, Vol. 14 Issue 7, p756 

    Understanding how differentiation programs originate from the gene-expression 'landscape' of hematopoietic stem cells (HSCs) is crucial for the development of new clinical therapies. We mapped the transcriptional dynamics underlying the first steps of commitment by tracking transcriptome changes...

  • Expression of the LIM-homeobox gene LH2 generates immortalized Steel factor-dependent multipotent hematopoietic precursors. Pinto do Ó, Perpetua; Kolterud, Åsa; Carlsson, Leif // EMBO Journal;10/1/98, Vol. 17 Issue 19, p5744 

    The genes controlling self-renewal and differentiation in the hematopoietic system are largely unknown. The LIM-homeobox genes are known to be important for asymmetric cell divisions and differentiation of specific cell types and organs. One member of this family, LH2, is expressed in fetal...

  • Driven Hematopoietic Differentiation of Embryonic Stem Cells: Epigenetic Perspectives. Tesarova, Lenka; Stejskal, Stanislav; Koutna, Irena // Current Pharmaceutical Design;Apr2014, Vol. 20 Issue 11, p1674 

    Hematopoietic progenitors derived from human embryonic stem cells (hESCs) present both a potential cell source for cellreplacement therapies and an in vitro model for hematopoietic stem cell (HSC) development. Current protocols for the hematopoietic differentiation of hESCs suffer from low...

  • Hematopoietic Stem Cells (HSC). Vohr, Hans-Werner // Encyclopedic Reference of Immunotoxicology;2005, p280 

    A definition of the term "hematopoietic stem cells" (HSC) is presented. It refers to a population of self-renewing cells committed to blood cell formation. Stem cells have the capacity to repopulate the blood forming and immune systems in irradiated hosts. HSC differentiate and generate...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics