October 2013
Pedijatrija Danas: Pediatrics Today;Oct2013, Vol. 9 Issue 2, p201
Academic Journal
Objective -- A description of the co-occurence of two rare paediatric neoplasias, and a discussion of the possible pathogenic processes and potential role of a tumour disposition syndrome. Case report -- We describe a 14 year old girl presenting with an abdominal mass which was found on resection to be a Leydig-Sertoli cell tumour. This was associated with a hepatic lesion suspected of a metastasis. Due to persistence despite chemotherapy the liver lesion was resected and confirmed to be a hepatocellular adenoma, providing the first reported co-occurrence of these rare neoplasms. Conclusion -- Hormonal activity of a Sertoli-Leydig cell tumour may predispose to hepatic adenoma, or the coincidence of these two tumours may be accounted for by a tumour predisposition syndrome. When investigating liver lesions the potential for an adenoma to mimic a metastasis should be considered.


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