TITLE

NEWBORN SCREENING PROGRAM FOR CONGENITAL HYPOTHYROIDISM IN MONTENEGRO

AUTHOR(S)
SAMARDŽIC, Mira; GLIGOROVIC-BARHANOVIC, Najdana; POPOVIC, Nataša; POPOVIC-SAMARDŽIC, Milena
PUB. DATE
October 2013
SOURCE
Pedijatrija Danas: Pediatrics Today;Oct2013, Vol. 9 Issue 2, p158
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objective -- The aim of this study was to assess the prevalence of congenital hypothyroidism (CH) over the last 5 years and analyze and summarize the status of newborn screening in Montenegro. Materials and methods -- This is a population-based retrospective study. Blood samples were collected from the heels of newborns 48 -- 96 hours after birth and thyroid-stimulating hormone (TSH) was determined. The cut of value in our laboratory was 10 mIU/l in whole blood. Dissociation-enhanced lanthanide fluorescent immunoassay (DELFIA) was used for detection. Results -- Over the period January 2008 -- December 2012, a total of 40,758 newborns were screened and 17 cases were confirmed as CH - both transient and permanent. The program covered all live born infants (100%). Recall rate was 0.97 -- 1.36%. Mean age of starting treatment was 21.4±6.4 days. Conclusion -- During the period of analysis in our study, 17 cases of CH were detected. he overall prevalence of CH was 1 in 2397 live births. his is the first report on newborn screening for congenital hypothyroidism in Montenegro.
ACCESSION #
91985156

 

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