TITLE

Occult Hematologic Malignancy in Routine Tonsillectomy Specimens

AUTHOR(S)
Booth, Cassie L.; Wang, Jun
PUB. DATE
December 2013
SOURCE
American Journal of Clinical Pathology;Dec2013, Vol. 140 Issue 6, p807
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Objectives: Handling of tonsillectomy specimens often includes gross and histologic examination. The published incidence of occult malignancy in benign-appearing tonsils is vanishingly rare, and consequently some propose omitting histologic analysis in young patients without clinical risk factors for malignancy or grossly suspicious features. Methods: At our institution, an occult Burkitt lymphoma in a grossly benign-appearing tonsil from an otherwise healthy 5-year-old prompted review of our cases. We retrospectively reviewed tonsillectomy findings over a 5-year period, excluding patients with known lymphoma or head and neck malignancies. A total of 740 patients were identified. All cases underwent gross and histologic examination. Results: Four additional malignancies were diagnosed, including a clinically unsuspected lymphoma in a 14-year-old patient. In our experience, although most tonsillar malignancies present with suspicious clinical or gross findings, occult malignancies do occur. Conclusions: Recognition of these occult findings may facilitate early diagnosis and treatment; thus pathologic study of these specimens may still be justified.
ACCESSION #
91961363

 

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