TITLE

Oxidative modification of fibrinogen molecules

AUTHOR(S)
Rosenfeld, M.; Shegolihin, A.; Bychkova, A.; Leonova, V.; Biryukova, M.; Kostanova, E.; Konstantinova, M.
PUB. DATE
September 2013
SOURCE
Doklady Biochemistry & Biophysics;Sep2013, Vol. 452 Issue 1, p255
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents a research that studies the different oxidative ability of fibrinogen domains D and E when exposed to reactive oxygen species (ROS) attack. Fibrinogen is a soluble plasma protein that is responsible for the formation of insoluble fibrin gel in the presence of thrombin. Also, many studies have shown that E region is more resistant to oxidation when exposed to ozone, as compared to D region.
ACCESSION #
91571261

 

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