Reproducción, envejecimiento y riesgo cardiovascular en el marco del ciclo vital de las mujeres

Bernis, Cristina
June 2013
Antropo;jun2013, Vol. 29, p9
Academic Journal
Numerous evidences suggest that early nutritional stress may increase metabolic and cardiovascular risk later in life, trough fetal programming. Recently, it has been suggested that women under nutritional stress during their reproductive life might experience a similar process. Normal physiological changes occurring to increase metabolic efficiency during pregnancy and breast-feeding could became permanent in stressful circumstances, (Thorugth a process similar fetus programming), and increase the risk of metabolic and cardiovascular risk later in life . Because of this, there is an increasing interest to understand to which extent reproductive life affects cardiovascular risk in women, and in which particular environmental circumstances. Using a cross -sectional sample of 1244 women aged 45-65, the predictive capacity of reproductive function for predicting cardiovascular risk profiles is evaluated, after adjusting for adiposity, other indicators of life cycle, socioeconomic and quality of life factors. Results show that both early sexual maturation, and advanced ovarian aging, significantly increase the risk for hypertension and hiperlipemias. No direct effects on cardiovascular risk have been detected for number of births or age at last maternity, however, results show indirect effects, mediated by adiposity.


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