TITLE

A STUDY ON ANTI-TUMOUR EFFECT OF SOLANUM LYRATUM THUNB. EXTRACT IN S180 TUMOUR-BEARING MICE

AUTHOR(S)
Yin Guan; Hong Zhao; Xiang Yan; Jing Meng; Weilan Wang
PUB. DATE
September 2013
SOURCE
African Journal of Traditional, Complementary & Alternative Medi;2013, Vol. 10 Issue 5, p345
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The objective of the study was to investigate the anti-tumour effect of ethanol extract of Solanum lyratum Thunb. in S180 tumour-bearing mice, and to preliminarily explore its mechanism of action. Methods: Mice were made into S180 solid tumour model, grouped and administered. Tumour inhibition rate was measured by harvesting the tumours. Serum IL-2, TNF-a contents were measured by taking blood samples, and thymus index and spleen index were measured by harvesting the thymus and spleen. The results showed that the Solanum lyratum Thunb. extract had certain tumour inhibitory effect, which can elevate the serum IL-2, TNF-a contents, and increase the thymus and spleen indices to a certain extent. The study concluded that Solanum lyratum Thunb. extract has certain in vivo anti-tumour effect which may be exerted through enhancing the body immunity.
ACCESSION #
90585452

 

Related Articles

  • Anti-microbial, Anti-oxidant and Anthelmintic Activity of Crude Extract of Solanum xanthocarpum. Priya, Pardhi; Pal, Jain Alok; Aditya, Ganeshpurkar; Gopal, Rai // Pharmacognosy Journal;7/1/2010, Vol. 2 Issue 11, p400 

    The aim of the present study was to evaluate the antimicrobial, anti-oxidant and anthelmintic potential of extracts of the herb Solanum xanthocarpum. The antimicrobial activity was tested against selected bacterial and fungal species by agar well diffusion method and the antioxidant activity was...

  • Effectiveness of ethanolic extract of Otostegia Persica against Plasmodium Berghei in comparison with chloriquine in white mice using in vivo tests. Nateghpour, M.; Miahipour, A.; Edirssian, Gh. H.; Sori, E.; Motevalli, A. // Journal of School of Public Health & Institute of Public Health ;2008, Vol. 6 Issue 1, p57 

    Background and Aim: Due to importance of employing native and traditional medicinal plants with good efficacy against malaria parasite, an ethanolic extract of Otostegia persica, was tested on Plasmodium berghei in sourian mice and a comparison was made with the effect of chloroquine on the same...

  • WOUND HEALING POTENTIAL OF SOME MEDICINAL PLANTS. Alam, Gulzar; Pratap Singh, Manjul; Singh, Anita // International Journal of Pharmaceutical Sciences Review & Resear;Jul/Aug2011, Vol. 9 Issue 1, p136 

    Wounds are inescapable events in life. Wounds may arise due to physical, chemical or microbial agents. Healing is survival mechanism and represents an attempt to maintain normal anatomical structure and function. Wound healing is a process by which tissue regeneration occurs. Plants and their...

  • QUALITY ASSESSMENT OF UNANI POLYHERBAL FORMULATION "HABB-E-AZARAQI" BY CONTEMPORARY SCIENTIFIC PARAMETERS. Yaqub, Shazad; Aftab, Mohd.; Asif, Mohd.; Yousuf, Peerzada Yasir // International Journal of Pharmaceutical Sciences & Research;Sep2013, Vol. 4 Issue 9, p3569 

    Demand of the Unani herbal drugs is becoming universal as the people are becoming more and more cognisant about the natural benefits of medicines with plant origin. Herbal drugs being easily affordable are becoming the first preference for the common man over purchasing the expensive modern...

  • HEPATOPROTECTIVE ACTIVITY OF PLANT BASED DRUGS AGAINST D-GALN. GUPTA, RAMJI; KUMAR, MUKESH; KUMAR, SOKINDAR; SINGH, SURYA PRAKASH; KUMAR, SAURABH // International Journal of Pharma & Bio Sciences;Jul2014, Vol. 5 Issue 3, pP-105 

    Liver disorder may cause liver inflammation or tissue injury and affects liver physiologic condition. Natural products that are found in the form of vegetables, fruits, plant extract, herbs, and animals, have been traditionally and clinically used for treating liver disorders. They are specific...

  • EVALUATION OF ANTIOXIDANT PROPERTIES AT DIFFERENT GERMINATION STAGES OF SEEDS OF NIGELLA SATIVA. KUSHWAH, DEVENDRA SINGH // International Journal of Pharma & Bio Sciences;Jul2014, Vol. 5 Issue 3, pP-472 

    Among the promising medicinal plants, Nigella sativa, also known as Black seeds and Black cumin, has been called the "Blessed Seed" for its miraculous curing ability. Present study has been carried out to evaluate anti-oxidant properties at different germination stages of seeds of Nigella...

  • Formulation and Evaluation of Moisturizer Containing Herbal Extracts for the Management of Dry Skin. Shweta, Kapoor; Swarnlata, Saraf // Pharmacognosy Journal;7/1/2010, Vol. 2 Issue 11, p409 

    Background Formulating a moisturizer using all natural raw materials is a formidable task. The Objective present paper focuses on the formulation of completely herbal moisturizers, their evaluation and comparison with commercial moisturizer. Methods Three of the herbal moisturizers [M1-M3]...

  • Ashwagandha, Stress and Anxiety Herb. Sahley, Billie J. // MMRC Health Educator Reports;2010, p1 

    The article focuses on the therapeutic use of the Indian herb, Ashwagandha. It states that Ashwagandha, which is used in ayurverdic medicine, strengthens deeper body tissues and increases quality body weight. It also indicates that the herb serves as an energy tonic for vegetarians and it is...

  • Crataegus oxyacantha Linn. commonly known as Hawthorn-A Scientific Review. Lakshmi, T.; Geetha, R. V.; Roy, Anitha // International Journal of PharmTech Research;Jan-Mar2012, Vol. 4 Issue 1, p458 

    Nature has been a source of medicinal agents for thousands of years and an impressive number of modern drugs has been isolated from natural sources, many based on their use in traditional medicine.Plant extracts are attractive sources of new drugs and have been shown to produce promising results...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics