TITLE

Effect of Ethanol Extract of Root Turnip (Brassica rapa) on Changes in Blood Factors HDL, LDL, Triglycerides and Total Cholesterol in Hypercholesterolemic Rabbits

AUTHOR(S)
Mirzaie, Hamide; Johari, Habibollah; Najafian, Mahmood; Kargar, Hossein
PUB. DATE
September 2012
SOURCE
Advances in Environmental Biology;Sep2012, Vol. 6 Issue 10, p2796
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Background: The expression of myocardial infarction and cerebral atherosclerosis is responsible for most cases in the United States and Western Europe. Research shows that over the past decade in most countries the use of alternative therapies and especially herbal therapy and dietary supplements to improve a variety of illnesses, including high blood fat, has increased. Therefore, the aim of this study is to investigate the effect of different doses of turnip juice on blood lipid changes in hypercholesterolemic rabbits. Methods: In this study, 30 adult female rabbits produced 5 to 6 equal groups: control, sham 1, sham 2, and treatments 1, 2 and 3 respectively. Extract at doses of 100, 200, 400 mg / kg body weight of the rabbits in groups 1, 2 and 3 with 1 g/kg cholesterol and 1 ml/kg of corn oil to the was given as gavage. Cholesterol group 1 and group 2 sham group received the same amount of corn oil. Studies were performed on blood factors and body weight changes and test data by ANOVA (One-way analysis of variance) at a significant level (P< 0/01) was determined by using SPSS version 15. Results: The results for total cholesterol in all treatment groups and one sham group were significantly increased. LDL in groups 1 and 2, and 1 have seen a significant increase compared with control requirements. HDL in the treatment group and sham 2 is a significant increase. Triglycerides in treatment group 1 and sham 1 is a significant increase compared to the control group (P< 0/01) .The body weight of the animals in the treatment groups, sham 1 and 2 has been significantly lower than the control group. The results shows that the turnip root extract can probably little that can prevent the occurrence of atherosclerotic due to flavonoids and vitamins in it.
ACCESSION #
90476842

 

Related Articles

  • Effect of Zingiber Officinale and Pistacia Veral Extract on Changes in Blood Factors HDL LDL, Triglycerides and Total Cholesterol in Hypercholesterolemic Rabbits. Tahmasebi, Fateme; Johari, Habibollah; Jahromi, Vahid Hemayatkhah; Rahmanian, Elham; Baghtiari, Adel; Farzam, Mohammad; Kargar, Hossein // Advances in Environmental Biology;Sep2012, Vol. 6 Issue 10, p2802 

    Introduction: the role of plants in reducing blood fats and thus reduces the risk of heart - Coronary known disease. The main aim of this study pistachio and ginger juice mixed effects on blood factors and atherosclerosis in adult rabbits. Methods: 30 adult female rabbits produced 5 to 6 equal...

  • Hypolipidemic and anti-atherogenic effects of vanadium in high-fat diet rabbits. Subrahmanyam, Gangapatnam; Sankar, Karuppiah Devi; Ramalingam, Krishnan; Bhanu, Ponnambalam Sharmila // Trace Elements & Electrolytes;2013 3rd Quarter, Vol. 30 Issue 3, p114 

    Effects of oral administration of vanadium on blood cholesterol level in relation to the cardio-protective functions is experimentally studied in New-Zealand white rabbits in the present study. The animals were divided into three groups of 8 animals each, Group 1 was fed standard diet, Group 2...

  • Cholesterol and triglyceride level guidelines.  // Functional U;Jan2004, Vol. 2 Issue 1, p7 

    Presents a chart comparing the U.S. and Canadian guidelines or standards for total cholesterol, low density lipoproteins, high density lipoproteins and triglyceride levels.

  • Antihyperlipidemic and Hepatoprotective Activity of Dodonaea viscosa Leaves Extracts in Alloxan-Induced Diabetic Rabbits (Oryctolagus cuniculus). Ahmad, Maqsood; Mahmood, Qaisar; Gulzar, Kamran; Akhtar, Muhammad Shoaib; Saleem, Mohammad; Qadir, Muhammad Imran // Pakistan Veterinary Journal;Jan-Mar2012, Vol. 32 Issue 1, p50 

    Hyperlipidemia is associated with diabetes and hepatotoxicity has emerged as a common clinical complication by antidiabetics. The present study was conducted to determine the antihyperlipidemic and hepatoprotective activity of Dodonaea viscosa leaves extracts in the alloxan-induced diabetic...

  • Effects of a Potent and Selective PPAR-a Agonist in Patients With Atherogenic Dyslipidemia or Hypercholesterolemia. Nissen, Steven E.; Nicholls, Stephen J.; Wolski, Kathy; Howey, Daniel C.; McErlean, Ellen; Wang, Ming-Dauh; Gomez, Elisa V.; Russo, John M. // JAMA: Journal of the American Medical Association;3/282007, Vol. 297 Issue 12, p1362 

    The article discusses the results of randomized controlled trials that examined the safety and efficacy of the drug LY518674, a peroxisome proliferator-activated receptor α agonist, in the treatment of patients with atherogenic dyslipidemia or hypercholesterolemia. Atherogenic dyslipidemia is...

  • Molecule of the Month. Felts, Andrew S. // Current Topics in Medicinal Chemistry;Sep2008, Vol. 8 Issue 14, p1310 

    The article focuses on Tredaptive, a nicotinic acid/laropiprant lipid-modifying therapy for the treatment of low density lipoprotein-cholesterol (LDL-C), high density lipoprotein-cholesterol (HDL-C) and triglycerides. It notes that the drug has been approved for use in treating patients with...

  • Cholesterol Guideline Changes. Wheaton, Jerry; Wright, John M. // Officer Review Magazine;Mar2006, Vol. 45 Issue 7, p23 

    The article presents guidelines about blood cholesterol. An accurate fasting blood test of total cholesterol is divided into the following: high-density lipoprotein fraction, low-density lipoprotein fraction and triglyceride. Statins are the first line of treatment for cholesterol reduction. If...

  • Cholesterol Update.  // Time;3/1/2010, Vol. 175 Issue 8, pS5 

    The article discusses the relationship between blood cholesterol levels and heart health. It distinguishes among high-density lipoprotein (HDL), low-density lipoprotein (LDL), and triglycerides, noting the risks posed by each. Regular exercise and prudent eating are promoted as the ways to meet...

  • Controlling Multiple Risk Factors Has a Cumulative Effect on Prevention of Recurrent Stroke. Spittler, Karen L. // Neurology Reviews;Jun2009, Vol. 17 Issue 6, p6 

    The article offers information on the study which investigates that optimal levels of low-density lipoproteins (LDL) cholesterol, high-density lipoproteins (HDL) cholesterol, triglycerides and blood pressure. It notes that LDL and HDL, as well as cholesterol and triglycerides reduce a person's...

Share

Read the Article

Courtesy of THE LIBRARY OF VIRGINIA

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics